Module 280 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0280 v02 0.58 -14.03
Displaying 1 - 16 of 16
Rv0960 Toxin 1, PIN domain

Details for Rv0960 - Toxin 1, PIN domain

GO Terms: GO:0040008

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0960

Tuberculist Genomic Region

Rv1294 Homoserine dehydrogenase (EC 1.1.1.3)

Details for Rv1294 - Homoserine dehydrogenase (EC 1.1.1.3)

GO Terms: GO:0004412, GO:0005886, GO:0040007

PATRIC Pathways: Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Lysine biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv1294

Tuberculist Genomic Region

Rv1700 ADP-ribose pyrophosphatase (EC 3.6.1.13)

Details for Rv1700 - ADP-ribose pyrophosphatase (EC 3.6.1.13)

GO Terms: GO:0047631, GO:0030145

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.16 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1700

Tuberculist Genomic Region

Rv1701 Tyrosine recombinase XerD

Details for Rv1701 - Tyrosine recombinase XerD

GO Terms: GO:0008150, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.21 | In vitro Essential: 0.15 | In vivo Essential: NA

Go to Gene Page: Rv1701

Tuberculist Genomic Region

Rv2081c

Details for Rv2081c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2081c

Tuberculist Genomic Region

Rv2082

Details for Rv2082 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.45 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2082

Tuberculist Genomic Region

Rv2083

Details for Rv2083 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2083

Tuberculist Genomic Region

Rv1200 Permeases of the major facilitator superfamily

Details for Rv1200 - Permeases of the major facilitator superfamily

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1200

Tuberculist Genomic Region

Rv1292 Arginyl-tRNA synthetase (EC 6.1.1.19)

Details for Rv1292 - Arginyl-tRNA synthetase (EC 6.1.1.19)

GO Terms: GO:0004814, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1292

Tuberculist Genomic Region

Rv1293 Diaminopimelate decarboxylase (EC 4.1.1.20)

Details for Rv1293 - Diaminopimelate decarboxylase (EC 4.1.1.20)

GO Terms: GO:0008836, GO:0005618, GO:0040007, GO:0042803, GO:0051289

PATRIC Pathways: Lysine biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv1293

Tuberculist Genomic Region

Rv1295 Threonine synthase (EC 4.2.3.1)

Details for Rv1295 - Threonine synthase (EC 4.2.3.1)

GO Terms: GO:0004795, GO:0004795, GO:0005829, GO:0005886, GO:0009088, GO:0030170, GO:0040007, GO:0042803

PATRIC Pathways: Vitamin B6 metabolism, Glycine, serine and threonine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1295

Tuberculist Genomic Region

Rv1699 CTP synthase (EC 6.3.4.2)

Details for Rv1699 - CTP synthase (EC 6.3.4.2)

GO Terms: GO:0003883, GO:0005886, GO:0040007

PATRIC Pathways: Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1699

Tuberculist Genomic Region

Rv2474c

Details for Rv2474c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.19 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2474c

Tuberculist Genomic Region

Rv2475c

Details for Rv2475c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.43 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2475c

Tuberculist Genomic Region

Rv2476c NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form

Details for Rv2476c - NAD-specific glutamate dehydrogenase (EC 1.4.1.2), large form

GO Terms: GO:0004354, GO:0005515, GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2476c

Tuberculist Genomic Region

Rv3200c Potassium channel protein

Details for Rv3200c - Potassium channel protein

GO Terms: GO:0005829, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.24 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3200c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 5 e-value: 20
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 21 of 21
GO:0040008 |

regulation of growth

GO:0004412 |

homoserine dehydrogenase activity

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0047631 |

ADP-ribose diphosphatase activity

GO:0030145 |

manganese ion binding

GO:0008150 |

biological_process

GO:0004814 |

arginine-tRNA ligase activity

GO:0005829 |

cytosol

GO:0008836 |

diaminopimelate decarboxylase activity

GO:0005618 |

cell wall

GO:0042803 |

protein homodimerization activity

GO:0051289 |

protein homotetramerization

GO:0004795 |

threonine synthase activity

GO:0009088 |

threonine biosynthetic process

GO:0030170 |

pyridoxal phosphate binding

GO:0003883 |

CTP synthase activity

GO:0004354 |

glutamate dehydrogenase (NADP+) activity

GO:0005515 |

protein binding

GO:0005887 |

integral to plasma membrane