Module 316 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0316 v02 0.52 -9.15
Displaying 1 - 21 of 21
Rv1435c \Probable conserved Proline, Glycine, Valine-rich secreted protein\\\""

Details for Rv1435c - \Probable conserved Proline, Glycine, Valine-rich secreted protein\\\""

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.38 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1435c

Tuberculist Genomic Region

Rv1566c Invasion protein

Details for Rv1566c - Invasion protein

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1566c

Tuberculist Genomic Region

Rv2145c FIG055075: Possibly a cell division protein, antigen 84 in Mycobacteria

Details for Rv2145c - FIG055075: Possibly a cell division protein, antigen 84 in Mycobacteria

GO Terms: GO:0005515, GO:0005618, GO:0005886, GO:0008360, GO:0009273, GO:0040007, GO:0050821, GO:0060187

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.11 | In vivo Essential: NA

Go to Gene Page: Rv2145c

Tuberculist Genomic Region

Rv2165c rRNA small subunit methyltransferase H

Details for Rv2165c - rRNA small subunit methyltransferase H

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv2165c

Tuberculist Genomic Region

Rv2166c Cell division protein MraZ

Details for Rv2166c - Cell division protein MraZ

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2166c

Tuberculist Genomic Region

Rv2525c Putative secreted protein

Details for Rv2525c - Putative secreted protein

GO Terms: GO:0005576, GO:0046677, GO:0008610

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2525c

Tuberculist Genomic Region

Rv2986c DNA-binding protein HU / low-complexity, AKP-rich domain

Details for Rv2986c - DNA-binding protein HU / low-complexity, AKP-rich domain

GO Terms: GO:0003677, GO:0005515, GO:0005618, GO:0005886, GO:0010106, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.16 | In vivo Essential: NA

Go to Gene Page: Rv2986c

Tuberculist Genomic Region

Rv3246c DNA-binding response regulator mtrA

Details for Rv3246c - DNA-binding response regulator mtrA

GO Terms: GO:0008150, GO:0008150, GO:0005886, GO:0006468, GO:0044117, GO:0045893

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.21

Go to Gene Page: Rv3246c

Tuberculist Genomic Region

Rv3258c

Details for Rv3258c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.09 | In vitro Essential: NA | In vivo Essential: 0.38

Go to Gene Page: Rv3258c

Tuberculist Genomic Region

Rv3413c

Details for Rv3413c -

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3413c

Tuberculist Genomic Region

Rv3414c RNA polymerase sigma-70 factor

Details for Rv3414c - RNA polymerase sigma-70 factor

GO Terms: GO:0009405, GO:0009408, GO:0016987, GO:0045893

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3414c

Tuberculist Genomic Region

Rv3587c

Details for Rv3587c -

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3587c

Tuberculist Genomic Region

Rv0430

Details for Rv0430 -

GO Terms: GO:0040007, GO:0046688

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.17 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv0430

Tuberculist Genomic Region

Rv0660c Prevent host death protein, Phd antitoxin

Details for Rv0660c - Prevent host death protein, Phd antitoxin

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.39 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0660c

Tuberculist Genomic Region

Rv0883c

Details for Rv0883c -

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.05 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv0883c

Tuberculist Genomic Region

Rv1497 Esterase LipL

Details for Rv1497 - Esterase LipL

GO Terms: GO:0004806

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1497

Tuberculist Genomic Region

Rv2927c Cell division initiation protein

Details for Rv2927c - Cell division initiation protein

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv2927c

Tuberculist Genomic Region

Rv3244c LpqB

Details for Rv3244c - LpqB

GO Terms: GO:0005576, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv3244c

Tuberculist Genomic Region

Rv3245c Sensor histidine kinase MtrB (EC 2.7.3.-)

Details for Rv3245c - Sensor histidine kinase MtrB (EC 2.7.3.-)

GO Terms: GO:0005829, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv3245c

Tuberculist Genomic Region

Rv3260c Sporulation regulatory protein WhiB

Details for Rv3260c - Sporulation regulatory protein WhiB

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3260c

Tuberculist Genomic Region

Rv3415c

Details for Rv3415c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.29 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3415c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.49 e-value: 70
Displaying 1 - 1 of 1
Histone protein Lsr2
regulates 12 modules
Weight: 
0.23
up-regulates
Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
regulates 24 modules
Weight: 
0.14
up-regulates
ESX-1 secreted protein regulator EspR
regulates 8 modules
Weight: 
0.14
up-regulates
regulates 14 modules
Weight: 
0.14
up-regulates
\transcriptional regulator, Crp/Fnr family\\\""
regulates 21 modules
Weight: 
-0.13
down-regulates
Transcriptional regulator, FUR family
regulates 9 modules
Weight: 
-0.12
down-regulates
Possible transcriptional regulatory protein
regulates 46 modules
Weight: 
0.11
up-regulates
putative two-component system response regulator
regulates 5 modules
Weight: 
0.11
up-regulates
Transcriptional regulator, TetR family
regulates 14 modules
Weight: 
0.09
up-regulates
Transcriptional regulator, TetR family
regulates 7 modules
Weight: 
0.08
up-regulates
Regulator of polyketide synthase expression
regulates 5 modules
Weight: 
0.08
up-regulates
\Transcriptional regulator, XRE family\\\""
regulates 2 modules
Weight: 
-0.06
down-regulates
Transcriptional regulator, GntR family
regulates 22 modules
Weight: 
0.05
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0009165 | GO:1901293 | GO:0009117 | GO:0016742 nucleotide biosynthetic process | nucleoside phosphate biosynthetic proces... | nucleotide metabolic process | hydroxymethyl-, formyl- and related tran...
Displaying 1 - 24 of 24
GO:0005576 |

extracellular region

GO:0005515 |

protein binding

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0008360 |

regulation of cell shape

GO:0009273 |

peptidoglycan-based cell wall biogenesis

GO:0040007 |

growth

GO:0050821 |

protein stabilization

GO:0060187 |

cell pole

GO:0046677 |

response to antibiotic

GO:0008610 |

lipid biosynthetic process

GO:0003677 |

DNA binding

GO:0010106 |

cellular response to iron ion starvation

GO:0008150 |

biological_process

GO:0006468 |

protein phosphorylation

GO:0044117 |

growth of symbiont in host

GO:0045893 |

positive regulation of transcription, DNA-dependent

GO:0009405 |

pathogenesis

GO:0009408 |

response to heat

GO:0016987 |

sigma factor activity

GO:0046688 |

response to copper ion

GO:0004806 |

triglyceride lipase activity

GO:0005829 |

cytosol