Rv0022c WhiB family transcriptional regulator

Rv0022c (WhiB family transcriptional regulator) is predicted to be co-regulated in modules bicluster_0211 with residual 0.50 and bicluster_0558 with residual 0.61.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.05 for bicluster_0211 and 0.00 and 0.69 for bicluster_0558 respectively.

These modules are enriched for following go terms: translation, non-membrane-bounded organelle, intracellular non-membrane-bounded organ..., organelle, intracellular organelle, cytoplasmic part response to stress, S-methyltransferase activity, O-acyltransferase activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 21 - 30 of 53
Gene Target Differential Expression Distance Expression pvalue Type
Type VII secretion integral membrane protein EccD
No -50 0.25 0.00295681 Primary.TSS
Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV
No -18 0.06 0.816528 Primary.TSS
Universal stress protein family
No 4 -0.21 0.683055 CDS
Induced -1 5.27 0 CDS
Induced 15 4.58 1.45e-31 Primary.TSS
Proteasome subunit alpha (EC 3.4.25.1), bacterial
No 33 0.07 0.699436 Internal.TSS
Proteasome subunit alpha (EC 3.4.25.1), bacterial
No 14 0.07 0.699436 Antisense.TSS
Carotene biosynthesis associated membrane protein
No 52 -0.26 0.102695 CDS
No 50 0.02 0.968866 CDS
Protein containing transglutaminase-like domain, putative cysteine protease
Induced 58 0.68 0.000928097 CDS
not assigned to any KEGG Pathway.
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 3.72 U
D3I 3 3 3.83 3.69 I
D3U 3 3 3.83 1.93 U
D5I 9 5 6.00 I
D5U 17 5 6.00 U
D7I 18 7 8.14 3.28 I
D7U 19 7 8.14 2.96 U
D14I 4 14 15.63 I
D14U 4 14 15.63 4.79 U
D17I 3 17 19.15 I
D17U 3 17 19.15 2.71 U
D21I 4 21 23.23 1.63 I
D21U 4 21 23.23 3.25 U
D24I 3 24 26.60 I
D24U 3 24 26.60 4.43 U
D28I 4 28 30.61 I
D28U 4 28 30.61 2.80 U