Rv0270 Long-chain-fatty-acid--CoA ligase (EC 188.8.131.52)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 20,000.00 and 33,000.00 for bicluster_0158 and 0.00 and 0.00 for bicluster_0397 respectively.
These modules are enriched for following go terms: pyruvate dehydrogenase activity, pyruvate dehydrogenase (acetyl-transferr..., oxidoreductase activity, acting on the a... nitrogen compound metabolic process, carbon-oxygen lyase activity.
This gene is found to be for growth on cholesterol.
|Product (LegacyBRC)||Product (RefSeq)|
|PROBABLE FATTY-ACID-CoA LIGASE FADD2 [FATTY-ACID-CoA SYNTHETASE] [FATTY-ACID-CoA SYNTHASE]||acyl-CoA synthetase|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.