Rv0458 Aldehyde dehydrogenase (EC 1.2.1.3)

Rv0458 (Aldehyde dehydrogenase (EC 1.2.1.3)) is predicted to be co-regulated in modules bicluster_0072 with residual 0.54 and bicluster_0438 with residual 0.51.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.32 for bicluster_0072 and 2.50 and 3,200.00 for bicluster_0438 respectively.

These modules are enriched for following go terms: porphyrin-containing compound metabolic ..., porphyrin-containing compound biosynthet..., cofactor biosynthetic process, sulfur amino acid biosynthetic process, sulfur amino acid metabolic process, cofactor metabolic process.

This gene is found to be for growth on cholesterol.

Mutant available?:

Locus Tag KEGG Pathways

KEGG

Glycerolipid metabolism

11
Total items in this category:  

KEGG

Pyruvate metabolism

40
Total items in this category:  

KEGG

Chloroalkane and chloroalkene degradation

13
Total items in this category:  

KEGG

Propanoate metabolism

62
Total items in this category:  

KEGG

Limonene and pinene degradation

65
Total items in this category:  

KEGG

Metabolic pathways

601
Total items in this category:  

KEGG

Biosynthesis of secondary metabolites

326
Total items in this category:  

KEGG

Microbial metabolism in diverse environments

296
Total items in this category:  
GO:0004029

aldehyde dehydrogenase (NAD) activity

aldehyde dehydrogenase (NAD) activity

Details: 
Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
GO Category: 
molecular_function
3
Total items in this category:  
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA