These modules are enriched for following go terms: .
This gene is found to be non-essential for growth on cholesterol.
|ChipSeq TF||Differential Expression||Distance||Expression||pvalue||Type|
|Product (LegacyBRC)||Product (RefSeq)|
|Putative uncharacterized protein|
|BioCyc Gene Page||Cellular Overview Map|
|No results were found|
|Cholesterol Essentiality||t-test p-value||Cholesterol/Glycerol Ratio|
How essentiality calculations were done?
The relative representation of each mutant was determined by calculating the fold change (sequence reads/insertion in cholesterol divided by sequence reads/insertion in glycerol) for each gene. Statistical significance was determined by t-test. Each insertion site in each replicate sample was treated as a separate data point. The hyperbola used for defining genes specifically required for growth in cholesterol was defined by the formula, y = 3.8/x+0.7. Genes above this line are annotated as required for growth on cholesterol.