Rv0653c Transcriptional regulator, TetR family

Rv0653c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0007 with residual 0.55 and bicluster_0043 with residual 0.47.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0007 and 0.00 and 0.01 for bicluster_0043 respectively.

These modules are enriched for following go terms: nucleic acid binding transcription facto..., sequence-specific DNA binding transcript....

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 19 of 19
Gene Target Differential Expression Distance Expression pvalue Type
PE family protein
No -114 0.03 0.93979 CDS
AAA family ATPase
No -123 -0.05 0.926151 CDS
Antitoxin of toxin-antitoxin stability system
No -26 -0.09 0.907296 Primary.TSS
Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)
No -148 0.12 0.589909 CDS
Multidrug resistance protein B
No 7 0.04 0.891731 Internal.TSS
PPE family protein
No 24 0.32 0.245002 Internal.TSS
Aspartate transaminase (EC 2.6.1.1)
No -124 -0.16 0.448646 Primary.TSS
monooxygenase, flavin-binding family
No -80 0.31 0.512947 CDS
monooxygenase, flavin-binding family
No -7 0.31 0.512947 Antisense.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 9.10 U
D3I 3 3 3.83 8.01 I
D3U 3 3 3.83 8.86 U
D5I 9 5 6.00 12.75 I
D5U 17 5 6.00 12.35 U
D7I 18 7 8.14 9.07 I
D7U 19 7 8.14 8.45 U
D14I 4 14 15.63 7.39 I
D14U 4 14 15.63 7.10 U
D17I 3 17 19.15 6.41 I
D17U 3 17 19.15 6.55 U
D21I 4 21 23.23 6.80 I
D21U 4 21 23.23 6.96 U
D24I 3 24 26.60 6.24 I
D24U 3 24 26.60 6.19 U
D28I 4 28 30.61 6.41 I
D28U 4 28 30.61 6.74 U