Rv0853c Pyruvate decarboxylase (EC 18.104.22.168); Alpha-keto-acid decarboxylase (EC 4.1.1.-)
Rv0853c (Pyruvate decarboxylase (EC 22.214.171.124); Alpha-keto-acid decarboxylase (EC 4.1.1.-)) is predicted to be co-regulated in modules bicluster_0048 with residual 0.53 and bicluster_0430 with residual 0.49.
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 3.40 and 37.00 for bicluster_0048 and 2,000.00 and 5,600.00 for bicluster_0430 respectively.
These modules are enriched for following go terms: primary metabolic process, cellular metabolic process, cellular process, organic substance metabolic process.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|Product (LegacyBRC)||Product (RefSeq)|
|Alpha-keto-acid decarboxylase||pyruvate or indole-3-pyruvate decarboxylase pdc|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.