Rv1353c Transcriptional regulator, TetR family

Rv1353c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0418 with residual 0.49 and bicluster_0511 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 7.60 for bicluster_0418 and 670.00 and 6,900.00 for bicluster_0511 respectively.

These modules are enriched for following go terms: phosphopantetheine binding, modified amino acid binding, amide binding, amino acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 91 - 100 of 238
Gene Target Differential Expression Distance Expression pvalue Type
No -41 0.54 0.0184396 Primary.TSS
S-adenosylmethionine synthetase (EC 2.5.1.6)
No 20 0.06 0.855752 Primary.TSS
Esterase/lipase
Repressed -11 -0.65 0.00414303 Primary.TSS
Esterase/lipase
No -55 -0.25 0.396865 Primary.TSS
YhhN family membrane protein
Repressed -5 -3.24 0 Primary.TSS
Methyltransferase
No -15 -0.1 0.916952 Primary.TSS
Methionyl-tRNA formyltransferase (EC 2.1.2.9)
No -98 0.12 0.839015 Primary.TSS
No -38 -0.32 0.292807 Internal.TSS
No -107 -0.32 0.292807 CDS
Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase
No -111 0.52 0.0256961 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.53 U
D3I 3 3 3.83 11.57 I
D3U 3 3 3.83 12.19 U
D5I 9 5 6.00 8.02 I
D5U 17 5 6.00 10.51 U
D7I 18 7 8.14 7.58 I
D7U 19 7 8.14 10.54 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.74 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 I
D21U 4 21 23.23 8.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 8.86 U
D28I 4 28 30.61 1.11 I
D28U 4 28 30.61 7.94 U