Rv1353c Transcriptional regulator, TetR family

Rv1353c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0418 with residual 0.49 and bicluster_0511 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 7.60 for bicluster_0418 and 670.00 and 6,900.00 for bicluster_0511 respectively.

These modules are enriched for following go terms: phosphopantetheine binding, modified amino acid binding, amide binding, amino acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 238
Gene Target Differential Expression Distance Expression pvalue Type
FIG034772: Probable conserved MCE associated protein
No -97 0.11 0.696539 Primary.TSS
Monoglyceride lipase (EC 3.1.1.23)
Repressed -7 -1.26 0.00000000000138 Primary.TSS
O-methyltransferase
No 52 -0.16 0.631111 Primary.TSS
Integral membrane protein, sugar transporter
No -62 -0.26 0.576682 CDS
PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
No 15 0.13 0.790055 Primary.TSS
Transcriptional regulator, TetR family
Repressed -7 -0.75 0.0234615 Primary.TSS
Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)
No 3 -0.03 0.957578 Primary.TSS
Nitrite reductase [NAD(P)H] small subunit (EC 1.7.1.4)
No -80 0.75 0.0793781 CDS
Induced 20 0.7 0.00258516 Primary.TSS
No results were found NA -10 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.53 U
D3I 3 3 3.83 11.57 I
D3U 3 3 3.83 12.19 U
D5I 9 5 6.00 8.02 I
D5U 17 5 6.00 10.51 U
D7I 18 7 8.14 7.58 I
D7U 19 7 8.14 10.54 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.74 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 I
D21U 4 21 23.23 8.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 8.86 U
D28I 4 28 30.61 1.11 I
D28U 4 28 30.61 7.94 U