Rv1994c Transcriptional regulator, ArsR family

Rv1994c (Transcriptional regulator, ArsR family) is predicted to be co-regulated in modules bicluster_0073 with residual 0.60 and bicluster_0337 with residual 0.50.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0073 and 0.00 and 0.00 for bicluster_0337 respectively.

These modules are enriched for following go terms: aspartate carbamoyltransferase activity.

This gene is found to be for growth on cholesterol.

Mutant available?: Yes

Displaying 51 - 60 of 69
Gene Target Differential Expression Distance Expression pvalue Type
Chorismate--pyruvate lyase (EC 4.1.3.40)
No -43 -0.37 0.340611 Primary.TSS
Possible membrane protein
No -121 0.18 0.645735 Antisense.TSS
PPE family protein
No -16 0.24 0.556151 CDS
Repressed -5 -1.36 9.2e-18 Primary.TSS
Probable response regulator
No -113 0.7 0.0985688 CDS
No 25 -0.45 0.182439 Primary.TSS
Repressed 25 -0.63 0.0112254 Internal.TSS
Histone acetyltransferase HPA2 and related acetyltransferases
No -41 0.09 0.775909 CDS
No 3 -0.66 0.145094 Primary.TSS
PPE family protein
No -8 0.48 0.0179626 Primary.TSS
not assigned to any KEGG Pathway.
GO:0010288

response to lead ion

response to lead ion

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
GO Category: 
biological_process
1
Total items in this category:  
GO:0016564

transcription repressor activity

transcription repressor activity

Details: 
OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.
GO Category: 
molecular_function
2
Total items in this category:  
GO:0032791

lead ion binding

lead ion binding

Details: 
Interacting selectively and non-covalently with lead (Pb) ions.
GO Category: 
molecular_function
1
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
GO:0046686

response to cadmium ion

response to cadmium ion

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
GO Category: 
biological_process
2
Total items in this category:  
GO:0046870

cadmium ion binding

cadmium ion binding

Details: 
Interacting selectively and non-covalently with cadmium (Cd) ions.
GO Category: 
molecular_function
2
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.86 U
D3I 3 3 3.83 13.72 I
D3U 3 3 3.83 14.28 U
D5I 9 5 6.00 10.48 I
D5U 17 5 6.00 12.38 U
D7I 18 7 8.14 10.13 I
D7U 19 7 8.14 13.44 U
D14I 4 14 15.63 6.80 I
D14U 4 14 15.63 13.42 U
D17I 3 17 19.15 4.03 I
D17U 3 17 19.15 13.51 U
D21I 4 21 23.23 4.95 I
D21U 4 21 23.23 13.33 U
D24I 3 24 26.60 2.76 I
D24U 3 24 26.60 13.28 U
D28I 4 28 30.61 4.96 I
D28U 4 28 30.61 12.95 U