Rv2066 Cobalt-precorrin-2 C20-methyltransferase (EC 126.96.36.199) / Cobalt-precorrin-3b C17-methyltransferase
|Symbol||Product||Feature Type||Start||End||Strand||Length||AA Length||is TF|
|Rv2066||cobI||Cobalt-precorrin-2 C20-methyltransferase (EC 188.8.131.52) / Cobalt-precorrin-3b C17-methyltransferase||CDS||2323175||2324701||+||1 527||508||FALSE|
Rv2066 (Cobalt-precorrin-2 C20-methyltransferase (EC 184.108.40.206) / Cobalt-precorrin-3b C17-methyltransferase) is predicted to be co-regulated in modules bicluster_0117 with residual 0.46 and bicluster_0474 with residual 0.57.
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 6,200.00 and 9,100.00 for bicluster_0117 and 0.24 and 18,000.00 for bicluster_0474 respectively.
These modules are enriched for following go terms: .
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|Product (LegacyBRC)||Product (RefSeq)|
|Cobalamin biosynthesis protein cobIJ||bifunctional S-adenosyl-L-methionine-precorrin-2 methyl transferase/precorrin-3 methylase Cob I/J|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.