Rv3249c Transcriptional regulator, TetR family

Rv3249c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0063 with residual 0.56 and bicluster_0167 with residual 0.51.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 37.00 for bicluster_0063 and 0.00 and 49.00 for bicluster_0167 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 101 - 110 of 129
Gene Target Differential Expression Distance Expression pvalue Type
WhiB-family transcriptional regulator
No -102 0.05 0.947657 Primary.TSS
dTDP-Rha:A-D-GlcNAc-diphosphoryl polyprenol, A-3-L-rhamnosyl transferase WbbL
No -27 0.06 0.776491 Antisense.TSS
Molybdenum cofactor biosynthesis protein MoaD / Molybdenum cofactor biosynthesis protein MoaE
No -10 -0.52 0.139758 Internal.TSS
Molybdenum cofactor biosynthesis protein MoaD / Molybdenum cofactor biosynthesis protein MoaE
No -19 -0.52 0.139758 CDS
Hydroxyproline-rich glycoprotein DZ-HRGP precursor
No -41 0.01 0.954928 Antisense.TSS
PPE family protein
No 60 0.27 0.376496 Primary.TSS
Cholesterol oxidase (EC 1.1.3.6)
Induced -20 1.62 0.000000000544 Primary.TSS
No -22 -0.31 0.186534 CDS
4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)
No -74 -0.2 0.637605 CDS
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)
No 60 -0.23 0.442182 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.44 U
D3I 3 3 3.83 13.39 I
D3U 3 3 3.83 13.06 U
D5I 9 5 6.00 13.87 I
D5U 17 5 6.00 13.73 U
D7I 18 7 8.14 13.67 I
D7U 19 7 8.14 13.15 U
D14I 4 14 15.63 11.79 I
D14U 4 14 15.63 11.70 U
D17I 3 17 19.15 10.81 I
D17U 3 17 19.15 10.88 U
D21I 4 21 23.23 10.36 I
D21U 4 21 23.23 11.06 U
D24I 3 24 26.60 9.00 I
D24U 3 24 26.60 9.91 U
D28I 4 28 30.61 8.76 I
D28U 4 28 30.61 10.03 U