Rv3291c Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system

Rv3291c (Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system) is predicted to be co-regulated in modules bicluster_0063 with residual 0.56 and bicluster_0561 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 37.00 for bicluster_0063 and 0.03 and 9.50 for bicluster_0561 respectively.

These modules are enriched for following go terms: monovalent inorganic cation transport, metal ion transport, cation-transporting ATPase activity, metal ion transmembrane transporter acti..., monovalent inorganic cation transmembran..., ATPase activity, coupled to transmembran....

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 14 of 14
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, AsnC family
No 1 0.39 0.370454 CDS
Transcriptional regulator, AsnC family
No 43 0.39 0.370454 Internal.TSS
Alanine dehydrogenase (EC 1.4.1.1)
No -44 -0.21 0.690019 Primary.TSS
Probable L-lysine-epsilon aminotransferase (EC 2.6.1.36) (L-lysine aminotransferase) (Lysine 6-aminotransferase)
Induced 44 2.69 4.51e-18 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0051260

protein homooligomerization

protein homooligomerization

Details: 
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO Category: 
biological_process
31
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.40 U
D3I 3 3 3.83 11.00 I
D3U 3 3 3.83 11.56 U
D5I 9 5 6.00 13.39 I
D5U 17 5 6.00 13.03 U
D7I 18 7 8.14 12.26 I
D7U 19 7 8.14 12.04 U
D14I 4 14 15.63 13.27 I
D14U 4 14 15.63 12.19 U
D17I 3 17 19.15 13.15 I
D17U 3 17 19.15 11.87 U
D21I 4 21 23.23 13.04 I
D21U 4 21 23.23 11.91 U
D24I 3 24 26.60 13.01 I
D24U 3 24 26.60 11.40 U
D28I 4 28 30.61 12.94 I
D28U 4 28 30.61 11.49 U