Rv3597c Histone protein Lsr2

Rv3597c (Histone protein Lsr2) is predicted to be co-regulated in modules bicluster_0140 with residual 0.62 and bicluster_0436 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0140 and 140.00 and 9,000.00 for bicluster_0436 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 184
Gene Target Differential Expression Distance Expression pvalue Type
Cell division protein DivIC (FtsB), stabilizes FtsL against RasP cleavage
No 17 -0.41 0.0536656 Internal.TSS
No 18 -0.03 0.970535 Primary.TSS
No -10 -0.44 0.368034 Primary.TSS
3-methylmercaptopropionyl-CoA dehydrogenase (DmdC)
No 42 0.45 0.585389 Primary.TSS
No -2 -0.19 0.725694 Primary.TSS
PPE family protein
No -146 -0.86 0.298879 Primary.TSS
Possible membrane protein
No 20 -0.06 0.926294 CDS
Transcriptional regulator, ArsR family
No -20 0.48 0.271291 CDS
Cytochrome P450 135A1
No 43 0.07 0.890683 CDS
HTH-type transcriptional regulator BetI
No -23 0.32 0.404455 Primary.TSS
Displaying 11 - 11 of 11
ChipSeq TF Differential Expression Distance Expression pvalue Type
Transcriptional regulator, ArsR family
No 61 0.5 0.0147616 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0005829

cytosol

cytosol

Details: 
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO Category: 
cellular_component
371
Total items in this category:  
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
GO:0006355

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

Details: 
Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
15
Total items in this category:  
GO:0010039

response to iron ion

response to iron ion

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
GO Category: 
biological_process
8
Total items in this category:  
GO:0040007

growth

growth

Details: 
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO Category: 
biological_process
621
Total items in this category:  
GO:0051260

protein homooligomerization

protein homooligomerization

Details: 
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO Category: 
biological_process
31
Total items in this category:  
Description:Expression data from transcription factor over expression experiments. TFOE are matched to the ChIP-seq experiment done simultaneously. This dataset is described in Rustad et al. 2014, Genome Biology.
BioProject Accession GEO Series References Repository Sample Method Sample Type
PRJNA254351 GSM1427018 GSE59086 25232098 GEO Tiling Array RNA
PRJNA254351 GSM1427019 GSE59086 25232098 GEO Tiling Array RNA
PRJNA254351 GSM1427016 GSE59086 25232098 GEO Tiling Array RNA
PRJNA254351 GSM1427017 GSE59086 25232098 GEO Tiling Array RNA
PRJNA254351 GSM1427018 GSE59086 25232098 GEO Tiling Array RNA
PRJNA254351 GSM1427019 GSE59086 25232098 GEO Tiling Array RNA
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D3U 3 3 3.83 11.81 U
D28I 4 28 30.61 12.08 I
D0U 27 0 0.00 12.23 U
D24I 3 24 26.60 12.35 I
D3I 3 3 3.83 12.54 I
D7I 18 7 8.14 12.54 I
D17I 3 17 19.15 12.58 I
D21I 4 21 23.23 12.68 I
D7U 19 7 8.14 13.00 U
D14I 4 14 15.63 13.04 I
D17U 3 17 19.15 13.67 U
D14U 4 14 15.63 13.70 U
D24U 3 24 26.60 13.82 U
D21U 4 21 23.23 13.83 U
D28U 4 28 30.61 14.28 U
D5U 17 5 6.00 14.34 U
D5I 9 5 6.00 14.38 I