Rv3597c Histone protein Lsr2

Rv3597c (Histone protein Lsr2) is predicted to be co-regulated in modules bicluster_0140 with residual 0.62 and bicluster_0436 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0140 and 140.00 and 9,000.00 for bicluster_0436 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 81 - 90 of 184
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, ArsR family
No 29 -0.17 0.639545 CDS
PPE family protein
No 36 -0.23 0.501225 Primary.TSS
oxidoreductase, FAD-binding
No -48 -0.15 0.751291 CDS
ESAT-6-like protein EsxL
No 11 0.1 0.909614 Primary.TSS
Type VII secretion integral membrane protein EccD
No -33 -0.16 0.160462 Primary.TSS
Drugs-transport transmembrane ATP-binding protein ABC transporter
No -43 0.48 0.390043 CDS
COG0028: Thiamine pyrophosphate-requiring enzymes
No -114 0.34 0.0498565 Primary.TSS
Esterase, secreted fibronectin-binding protein antigen 85-B FbpB
No 52 -0.23 0.566987 Primary.TSS
2-nitropropane dioxygenase (EC 1.13.11.32)
No -5 0.19 0.667367 Primary.TSS
Monooxygenase component A
No -54 0.16 0.803954 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0005618

cell wall

cell wall

Details: 
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
GO Category: 
cellular_component
320
Total items in this category:  
GO:0005829

cytosol

cytosol

Details: 
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO Category: 
cellular_component
371
Total items in this category:  
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
GO:0006355

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

Details: 
Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
15
Total items in this category:  
GO:0010039

response to iron ion

response to iron ion

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
GO Category: 
biological_process
8
Total items in this category:  
GO:0040007

growth

growth

Details: 
The increase in size or mass of an entire organism, a part of an organism or a cell.
GO Category: 
biological_process
621
Total items in this category:  
GO:0051260

protein homooligomerization

protein homooligomerization

Details: 
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
GO Category: 
biological_process
31
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D3I 3 3 3.83 12.54 I
D3U 3 3 3.83 11.81 U
D17I 3 17 19.15 12.58 I
D17U 3 17 19.15 13.67 U
D24I 3 24 26.60 12.35 I
D24U 3 24 26.60 13.82 U
D28I 4 28 30.61 12.08 I
D28U 4 28 30.61 14.28 U
D14I 4 14 15.63 13.04 I
D14U 4 14 15.63 13.70 U
D21I 4 21 23.23 12.68 I
D21U 4 21 23.23 13.83 U
D5I 9 5 6.00 14.38 I
D5U 17 5 6.00 14.34 U
D7I 18 7 8.14 12.54 I
D7U 19 7 8.14 13.00 U
D0U 27 0 0.00 12.23 U