Rv3634c UDP-glucose 4-epimerase (EC 22.214.171.124)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 65.00 and 550.00 for bicluster_0414 and 0.02 and 25.00 for bicluster_0493 respectively.
These modules are enriched for following go terms: .
This gene is found to be non-essential for growth on cholesterol.
|Product (LegacyBRC)||Product (RefSeq)|
|UDP-GLUCOSE 4-EPIMERASE GALE1 [GALACTOWALDENASE] [UDP-GALACTOSE 4-EPIMERASE] [URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE] [URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE]||UDP-glucose 4-epimerase GALE1 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase)|
|BioCyc Gene Page||Cellular Overview Map|
UDP-glucose 4-epimerase activity
|No results were found|
|Cholesterol Essentiality||t-test p-value||Cholesterol/Glycerol Ratio|
How essentiality calculations were done?
The relative representation of each mutant was determined by calculating the fold change (sequence reads/insertion in cholesterol divided by sequence reads/insertion in glycerol) for each gene. Statistical significance was determined by t-test. Each insertion site in each replicate sample was treated as a separate data point. The hyperbola used for defining genes specifically required for growth in cholesterol was defined by the formula, y = 3.8/x+0.7. Genes above this line are annotated as required for growth on cholesterol.