Rv3873 Putative ESX-1 secretion system gating protein PPE68
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.06 and 2,000.00 for bicluster_0243 and 0.00 and 0.00 for bicluster_0559 respectively.
These modules are enriched for following go terms: Mo-molybdopterin cofactor biosynthetic p..., Mo-molybdopterin cofactor metabolic proc..., molybdopterin cofactor biosynthetic proc..., molybdopterin cofactor metabolic process, prosthetic group metabolic process.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|BASS Score||Re-Annotated Start||Tuberculist Annotated Start|
|Product (LegacyBRC)||Product (RefSeq)|
|PPE FAMILY PROTEIN||PPE family protein|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.