Publications
Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis." Nat Microbiol. 2016;1(8):16078.
"Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation." Molecular Systems Biology. 2019;15:e8584.
"Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine." Nat. Med.. 2018;24(2):130-143.
"Prospective Discrimination of Controllers From Progressors Early After Low-Dose Mycobacterium tuberculosis Infection of Cynomolgus Macaques using Blood RNA Signatures." J. Infect. Dis.. 2018;217(8):1318-1322.
"Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease." PLoS Pathog.. 2017;13(11):e1006687.
"Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung." Mucosal Immunol. 2017;10(2):555-564.
"Systems integration of innate and adaptive immunity." Vaccine. 2015;33(40):5241-8.
"Systems proteomics approaches to study bacterial pathogens: application to Mycobacterium tuberculosis." Curr. Opin. Microbiol.. 2017;39:64-72.
"Systems-level analysis of innate immunity." Annu. Rev. Immunol.. 2014;32:547-77.
"TB vaccines; promoting rapid and durable protection in the lung." Curr. Opin. Immunol.. 2015;35:55-62.
"Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis." Nat Microbiol. 2020.
"Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis." mBio. 2019;10(6).
"Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis." Cell Host Microbe. 2020.
"Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis." Semin. Immunol.. 2014;26(6):578-87.
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