P9WG75 thiE, Rv0414c, MTCY22G10.11c | MTB Network Portal

Summary

Source: Uniprot proteome:up000001584

Title	id	ORF names	Protein names	PubMed ID	Short	Synonyms	EnsemblBacteria
P9WG75 THIE_MYCTU	Rv0414c Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	MTCY22G10.11c	Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase)	9634230, 14569030, 21818324,	thiE	thiE, Rv0414c, MTCY22G10.11c

Structure Details

Binding Site
81 81 HMP-PP (By similarity)., 120 120 HMP-PP (By similarity)., 149 149 HMP-PP (By similarity)., 178 178 THZ-P, via amide nitrogen (By similarity).

Domain/Family Details

InterPro	Pfam	ProDom	Region	Similarity	SUPFAM
	PF02581			Belongs to the thiamine-phosphate synthase family.	SSF51391

Domain/Family DBs

Gene3D	HAMAP	PANTHER	Pfam	PIRSF	PRINTS	ProDom	PROSITE	SMART	SUPFAM
3.20.20.70,	MF_00097,		PF02581						SSF51391

SSGCID Target Details

SSGCID ID

3D Details

PDB	Protein Model Portal

Pathway Details

EC number	KEGG KO	UniPathway
2.5.1.3		Cofactor biosynthesis, thiamine diphosphate biosynthesis, thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.

Phylogenetic

HOGENOM	KEGG KO	OMA	OrthoDB