Genes
Gene annotations were collated from multiple sources;
- MaGe MicroScope Publication: PMID:21349987
- Uniprot
- PATRIC
Gene essentiality is based on TnSeq Data from: Dembek M, Barquist L, Boinett CJ, et al. High-throughput analysis of gene essentiality and sporulation in Clostridium difficile. mBio. 2015;6(2):e02383. Published 2015 Feb 24.doi:10.1128/mBio.02383-14
| Title | Short Name | Product | Essentiality(TnSeq) | Essentiality(in vivo) | Essentiality(Rich Broth) | Expression | |
|---|---|---|---|---|---|---|---|
| CD630_07150 | ptb | Phosphate butyryltransferase(Phosphotransbutyrylase) |
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| CD630_07160 | cooS | Bifunctional carbon monoxidedehydrogenase/acetyl-CoA synthase (CODH) |
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| CD630_07170 | Bifunctional carbon monoxidedehydrogenase/acetyl-CoA synthase, accessory protein |
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| CD630_07180 | fhs | Formate--tetrahydrofolate ligase(Formyltetrahydrofolate synthetase) (FHS) (FTHFS) | Yes |
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| CD630_07190 | fchA | Methenyltetrahydrofolate cyclohydrolase(5,10-methenyltetrahydrofolate 5-hydrolase) | Yes |
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| CD630_07200 | folD | Bifunctional protein folD [Includes:Methylenetetrahydrofolate dehydrogenase ;Methenyltetrahydrofolate cyclohydrolase] | Yes | Yes |
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| CD630_07210 | Conserved hypothetical protein |
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| CD630_07220 | metF | 5,10-methylenetetrahydrofolate reductase |
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| CD630_07230 | Bifunctional carbon monoxidedehydrogenase/acetyl-CoA synthase, dihydrolipoyldehydrogenase subunit |
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| CD630_07240 | Bifunctional carbon monoxidedehydrogenase/acetyl-CoA synthase,nickel-inserting subunit |
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