Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 1 - 10 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_28	16 CD630_00780 - rplV Type: Gene Product:50S ribosomal protein L22 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00870 - rplR Type: Gene Product:50S ribosomal protein L18 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00730 - rplC Type: Gene Product:50S ribosomal protein L3 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00790 - rpsC Type: Gene Product:30S ribosomal protein S3 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00890 - rplO Type: Gene Product:50S ribosomal protein L15 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00950 - rpsM Type: Gene Product:30S ribosomal protein S13 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00940 - infA Type: Gene Product:Translation initiation factor IF-1 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00740 - rplD Type: Gene Product:50S ribosomal protein L4 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00900 - prlA Type: Gene Product:Preprotein translocase SecY subunit \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_01040 - rplM Type: Gene Product:50S ribosomal protein L13 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00770 - rpsS Type: Gene Product:30S ribosomal protein S19 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00700 - fusA Type: Gene Product:Elongation factor G (EF-G) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00920 - map1 Type: Gene Product:Methionine aminopeptidase Map1 (MAP) (PeptidaseM) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00910 - adk Type: Gene Product:Adenylate kinase \| Pathway: Purine metabolism \| COG: Nucleotide transport and metabolism CD630_00820 - rplN Type: Gene Product:50S ribosomal protein L14 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00930 - Type: Gene Product:Ribosomal protein L14E/L6E/L27E-like \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.12	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_197	28 CD630_19401 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_05821 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_27341 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_29341 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_22952 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_03181 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06941 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_22242 - Type: Gene Product:Putative extrachromosomal origin protein \| Pathway: \| COG: CD630_12371 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12332 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_02921 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_09241 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_12334 - Type: Gene Product:Fragment of putative phage antirepressor protein(part 2) \| Pathway: \| COG: CD630_26811 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_15160 - Type: Gene Product:Transcriptional regulator, MerR family \| Pathway: \| COG: Transcription CD630_24351 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_21152 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_05921 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: CD630_34531 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_17281 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_19491 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_28181 - Type: Gene Product:Fragment of dihydrofolate reductase familyprotein \| Pathway: \| COG: CD630_05211 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12341 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_06230 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_20060 - Type: Gene Product:Fragment of putative topoisomerase (C-terminalregion) \| Pathway: \| COG: Function unknown CD630_15152 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_01811 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	1.4	`NA`	0.13	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_15160 - Type: Gene Product:Transcriptional regulator, MerR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_277	16 CD630_t0520 - tRNA-Tyr Type: Gene Product: \| Pathway: \| COG: CD630_t0590 - tRNA-Pro Type: Gene Product: \| Pathway: \| COG: CD630_t0630 - tRNA-Phe Type: Gene Product: \| Pathway: \| COG: CD630_t0220 - tRNA-Cys Type: Gene Product: \| Pathway: \| COG: CD630_t0100 - tRNA-Thr Type: Gene Product: \| Pathway: \| COG: CD630_t0620 - tRNA-Ile Type: Gene Product: \| Pathway: \| COG: CD630_t0250 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0850 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_00200 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_t0840 - tRNA-Thr Type: Gene Product: \| Pathway: \| COG: CD630_t0610 - tRNA-Pro Type: Gene Product: \| Pathway: \| COG: CD630_t0640 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0050 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0600 - tRNA-Trp Type: Gene Product: \| Pathway: \| COG: CD630_t0490 - tRNA-Val Type: Gene Product: \| Pathway: \| COG: CD630_t0680 - tRNA-Met Type: Gene Product: \| Pathway: \| COG:	0	0	0.14	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_10090 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_14070 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_79	15 CD630_00780 - rplV Type: Gene Product:50S ribosomal protein L22 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_01050 - rpsI Type: Gene Product:30S ribosomal protein S9 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00870 - rplR Type: Gene Product:50S ribosomal protein L18 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00820 - rplN Type: Gene Product:50S ribosomal protein L14 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00790 - rpsC Type: Gene Product:30S ribosomal protein S3 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00830 - rplX Type: Gene Product:50S ribosomal protein L24 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00950 - rpsM Type: Gene Product:30S ribosomal protein S13 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00940 - infA Type: Gene Product:Translation initiation factor IF-1 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00860 - rplF Type: Gene Product:50S ribosomal protein L6 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00740 - rplD Type: Gene Product:50S ribosomal protein L4 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00900 - prlA Type: Gene Product:Preprotein translocase SecY subunit \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_00750 - rplW Type: Gene Product:50S ribosomal protein L23 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00770 - rpsS Type: Gene Product:30S ribosomal protein S19 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00810 - rpsQ Type: Gene Product:30S ribosomal protein S17 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00980 - rpoA Type: Gene Product:DNA-directed RNA polymerase subunit alpha \| Pathway: \| COG: Transcription	`NA`	`NA`	0.14	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_11770 - fapR Type: Gene Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) \| Pathway: \| COG: Transcription CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_133	21 CD630_t0460 - tRNA-Ala Type: Gene Product: \| Pathway: \| COG: CD630_33430 - Type: Gene Product:Putative replication initiation factorTn916-like, CTn6-Orf21 \| Pathway: \| COG: Replication, recombination and repair CD630_t0350 - tRNA-Gln Type: Gene Product: \| Pathway: \| COG: CD630_33872 - Type: Gene Product:Fragment of conjugative transposon proteinTn916-like, CTn7-Orf26 (C-terminal region) \| Pathway: \| COG: CD630_t0060 - tRNA-Glu Type: Gene Product: \| Pathway: \| COG: CD630_t0810 - tRNA-Leu Type: Gene Product: \| Pathway: \| COG: CD630_t0530 - tRNA-Gly Type: Gene Product: \| Pathway: \| COG: CD630_33421 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf20 \| Pathway: \| COG: Function unknown CD630_t0360 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_t0420 - tRNA-Lys Type: Gene Product: \| Pathway: \| COG: CD630_33781 - Type: Gene Product:Fragment of putative transcriptional regulatorTn916-like, CTn7-Orf14 (Central region) \| Pathway: \| COG: Transcription CD630_t0550 - tRNA-Gln Type: Gene Product: \| Pathway: \| COG: CD630_t0260 - tRNA-Glu Type: Gene Product: \| Pathway: \| COG: CD630_t0660 - tRNA-Ala Type: Gene Product: \| Pathway: \| COG: CD630_t0180 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0200 - tRNA-His Type: Gene Product: \| Pathway: \| COG: CD630_20103 - Type: Gene Product:Fragment of conserved hypothetical protein(Central region, Part 2) \| Pathway: \| COG: Function unknown, Function unknown CD630_19820 - Type: Gene Product:Fragment of putative phenazine biosynthesisprotein (Part 1) \| Pathway: \| COG: Function unknown, Function unknown CD630_t0730 - tRNA-Glu Type: Gene Product: \| Pathway: \| COG: CD630_t0160 - tRNA-Phe Type: Gene Product: \| Pathway: \| COG: CD630_22841 - Type: Gene Product:Fragment of putative beta-lactamase inducer(C-terminal region) \| Pathway: \| COG:	0	0	0.17	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_32600 - phoU Type: Gene Product:Phosphate uptake regulator, PhoU \| Pathway: \| COG: Inorganic ion transport and metabolism TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_298	18 CD630_09900 - leuC Type: Gene Product:3-isopropylmalate dehydratase large subunit \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_15810 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_23640 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_05740 - thrS Type: Gene Product:Threonyl-tRNA synthetase \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_23650 - Type: Gene Product:ABC-type transport system,nitrate/sulfonate/taurine extracellular solute-bindingprotein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_07010 - Type: Gene Product:Putative cell-division protein \| Pathway: \| COG: Function unknown CD630_23670 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_09910 - leuD Type: Gene Product:3-isopropylmalate dehydratase small subunit \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_23610 - Type: Gene Product:ABC-type transport system,nitrate/sulfonate/taurine ATP-binding protein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_23630 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_09890 - leuA Type: Gene Product:2-isopropylmalate synthase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_23600 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_15800 - hom2 Type: Gene Product:Homoserine dehydrogenase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_09920 - leuB Type: Gene Product:3-isopropylmalate dehydrogenase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_07000 - pheT Type: Gene Product:Phenylalanyl-tRNA synthetase subunit beta(Phenylalanine--tRNA ligase beta chain) (PheRS) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_23660 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_06990 - pheS Type: Gene Product:Phenylalanyl-tRNA synthetase alpha chain(Phenylalanine--tRNA ligase alpha chain) (PheRS) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_23680 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown	0.000000026	0.04	0.20	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_158	13 CD630_19110 - eutW Type: Gene Product:Two-component sensor histidine kinase,Ethanolamine specific \| Pathway: \| COG: Signal transduction mechanisms CD630_19160 - eutK Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_19130 - eutB Type: Gene Product:Ethanolamine ammonia lyase large subunit \| Pathway: \| COG: Amino acid transport and metabolism CD630_19120 - eutA Type: Gene Product:Ethanolamine reactivating factor for ammonialyase eutBC \| Pathway: \| COG: Amino acid transport and metabolism CD630_19080 - eutS Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_19100 - eutV Type: Gene Product:Two-component response regulator, Ethanolaminespecific \| Pathway: \| COG: Signal transduction mechanisms CD630_19090 - eutP Type: Gene Product:Ethanolamine utilization protein, GTPase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_19210 - Type: Gene Product:Putative ethanolamine utilization protein \| Pathway: \| COG: Function unknown CD630_19070 - eutG Type: Gene Product:Ethanolamine iron-dependent Alcoholdehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_19180 - eutM Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_19140 - eutC Type: Gene Product:Ethanolamine ammonia lyase small subunit \| Pathway: Amine and polyamine degradation \| COG: Amino acid transport and metabolism CD630_19220 - eutN Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_19150 - eutL Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism	1.8	`NA`	0.21	Inferelator: 1 Hypergeometric: 1 TF Influences from Inferelator CD630_19100 - eutV Type: Gene Product:Two-component response regulator, Ethanolaminespecific \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test CD630_32450 - prdR Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription
Module_80	30 CD630_20431 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_31563 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_31562 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_21501 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_20750 - pbuX Type: Gene Product:Putative xanthine permease \| Pathway: \| COG: Nucleotide transport and metabolism CD630_15152 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06011 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_19871 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12371 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12333 - Type: Gene Product:Fragment of putative phage antirepressor protein(part 1) \| Pathway: \| COG: CD630_12332 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_16631 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06230 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_02000 - Type: Gene Product:Fragment of transcriptional regulator, LysRfamily (C-terminal region) \| Pathway: \| COG: Transcription CD630_06210 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_30610 - Type: Gene Product:PTS system, alpha-glucoside-specific IIBCcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_21152 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_32561 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_04350 - Type: Gene Product:Putative sigma factor Tn1549-like, CTn2-Orf31 \| Pathway: \| COG: Function unknown CD630_12381 - Type: Gene Product:Fragment of conserved hypothetical protein \| Pathway: \| COG: CD630_20071 - Type: Gene Product:Fragment of conserved hypothetical protein(N-terminal region) \| Pathway: \| COG: Transcription CD630_02671 - Type: Gene Product:Putative flagellar protein \| Pathway: \| COG: CD630_21631 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_19491 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_05211 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06240 - Type: Gene Product:Putative transcriptional regulator, activatorMor \| Pathway: \| COG: Transcription CD630_21021 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_05921 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: CD630_06941 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_33271 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf3 \| Pathway: \| COG:	0.08	`NA`	0.21	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_31200 - Type: Gene Product:Transcriptional regulator, AbrB family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_161	18 CD630_15000 - tlpB Type: Gene Product:Transposase-like protein B \| Pathway: \| COG: Replication, recombination and repair CD630_01620 - Type: Gene Product:Putative radical SAM-family protein \| Pathway: \| COG: Function unknown CD630_18210 - tlpB Type: Gene Product:Transposase-like protein B \| Pathway: \| COG: Replication, recombination and repair CD630_00010 - dnaA Type: Gene Product:Chromosomal replication initiator protein \| Pathway: \| COG: Replication, recombination and repair CD630_01630 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_13120 - tlpB Type: Gene Product:Transposase-like protein B \| Pathway: \| COG: Replication, recombination and repair CD630_26640 - murE Type: Gene Product:UDP-N-acetylmuramyl-tripeptide synthetase \| Pathway: Cell wall biogenesis \| COG: Cell wall/membrane/envelope biogenesis CD630_13170 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_26650 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_01610 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_00100 - rsbW Type: Gene Product:Serine-protein kinase RsbW \| Pathway: \| COG: Signal transduction mechanisms CD630_17190 - tlpB Type: Gene Product:Transposase-like protein B \| Pathway: \| COG: Replication, recombination and repair CD630_08170 - tlpB Type: Gene Product:Transposase-like protein B \| Pathway: \| COG: Replication, recombination and repair CD630_13180 - pnp Type: Gene Product:Polyribonucleotide nucleotidyltransferase \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11350 - Type: Gene Product:Putative SH3-domain protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11340 - gloA Type: Gene Product:Lactoylglutathione lyase \| Pathway: \| COG: Amino acid transport and metabolism CD630_11360 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_00080 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	1.1e-21	1.9e-18	0.21	Inferelator: 4 Hypergeometric: 0 TF Influences from Inferelator CD630_05590 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_10090 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_16920 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_16930 - Type: Gene Product:Putative dinitrogenase iron-molybdenum cofactor \| Pathway: \| COG: Function unknown TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_317	14 CD630_00750 - rplW Type: Gene Product:50S ribosomal protein L23 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00880 - rpsE Type: Gene Product:30S ribosomal protein S5 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00810 - rpsQ Type: Gene Product:30S ribosomal protein S17 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00720 - rpsJ Type: Gene Product:30S ribosomal protein S10 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00860 - rplF Type: Gene Product:50S ribosomal protein L6 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_01050 - rpsI Type: Gene Product:30S ribosomal protein S9 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00830 - rplX Type: Gene Product:50S ribosomal protein L24 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00990 - rplQ Type: Gene Product:50S ribosomal protein L17 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_01040 - rplM Type: Gene Product:50S ribosomal protein L13 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00980 - rpoA Type: Gene Product:DNA-directed RNA polymerase subunit alpha \| Pathway: \| COG: Transcription CD630_22121 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_00700 - fusA Type: Gene Product:Elongation factor G (EF-G) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00920 - map1 Type: Gene Product:Methionine aminopeptidase Map1 (MAP) (PeptidaseM) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00930 - Type: Gene Product:Ribosomal protein L14E/L6E/L27E-like \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.22	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_04500 - Type: Gene Product:Putative transcriptional regulator \| Pathway: \| COG: Transcription CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`