Exponential to stationary phase
Conditions
| Title | Description | Overall Design | Pubmed ID | Samples | Series ID | Summary | Type |
|---|---|---|---|---|---|---|---|
| Exponential to stationary phase |
Metabolic reprogramming with the induction of toxin production of Clostridioides difficile during the stationary phase |
Clostridioides difficile 630∆erm (DSM28645) were grown in a casamino acids medium (CDMM) containing 2 g/L glucose. Samples were taken at five time points along the growth curve (exponential growth: 14.5 h of cultivation, transient phase: 17.25 h, stationary phase 1: 19.25 h, stationary phase 2: 24.25 h, stationary phase 3: 29.25 h). The cultivation was performed with four biological replicates. Reference in transcriptomic acid proteomic measurement was the exponential phase samples. | GSM3164188 , GSM3164189 , GSM3164190 , GSM3164191 , GSM3164192 , GSM3164193 , GSM3164194 , GSM3164195 , GSM3164196 , GSM3164197 , GSM3164198 , GSM3164199 , GSM3164200 , GSM3164201 , GSM3164202 , GSM3164203 | GSE115054 | Systems biology approach of Clostridioides difficile to analyze the temporal changes in the intracellular and extracellular metabolme, transcriptome and proteome along the growth curve in casamino acids medium and the connection to toxin production. | Expression profiling by array |