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- protein polyubiquitination
- DNA binding
- RNA binding
- ubiquitin-protein ligase activity
- protein binding
- intracellular
- nucleus
- cytoplasm
- protein monoubiquitination
- cell cycle
- zinc ion binding
- protein ubiquitination
- ligase activity
- SCF ubiquitin ligase complex
- ribonucleoprotein complex
- protein destabilization
- negative regulation of NF-kappaB transcription factor activity
- positive regulation of cell cycle
- metal ion binding
- protein autoubiquitination
- protein trimerization
- negative regulation of protein deubiquitination
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