Module 572 Residual: 0.62

Title Bicluster Model Residual Score
bicluster_0572 v02 0.62 -21.82
Displaying 1 - 15 of 15
Rv0183 Monoglyceride lipase (EC 3.1.1.23)

Details for Rv0183 - Monoglyceride lipase (EC 3.1.1.23)

GO Terms: GO:0047372, GO:0005618, GO:0005886, GO:0047372, GO:0004622

PATRIC Pathways: Glycerolipid metabolism

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0183

Tuberculist Genomic Region

Rv0741 Mobile element protein

Details for Rv0741 - Mobile element protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0741

Tuberculist Genomic Region

Rv1201c 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117)

Details for Rv1201c - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117)

GO Terms: GO:0008666, GO:0000287, GO:0005886, GO:0008666, GO:0031402, GO:0040007, GO:0050662, GO:0051260, GO:0070207

PATRIC Pathways: Lysine biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv1201c

Tuberculist Genomic Region

Rv1387 PPE family protein

Details for Rv1387 - PPE family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1387

Tuberculist Genomic Region

Rv1657 Arginine pathway regulatory protein ArgR, repressor of arg regulon

Details for Rv1657 - Arginine pathway regulatory protein ArgR, repressor of arg regulon

GO Terms: GO:0003677, GO:0051260

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1657

Tuberculist Genomic Region

Rv2061c

Details for Rv2061c -

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2061c

Tuberculist Genomic Region

Rv2139 Dihydroorotate dehydrogenase (EC 1.3.3.1)

Details for Rv2139 - Dihydroorotate dehydrogenase (EC 1.3.3.1)

GO Terms: GO:0004158, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2139

Tuberculist Genomic Region

Rv2603c

Details for Rv2603c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2603c

Tuberculist Genomic Region

Rv2793c tRNA pseudouridine synthase B (EC 4.2.1.70)

Details for Rv2793c - tRNA pseudouridine synthase B (EC 4.2.1.70)

GO Terms: GO:0005618

PATRIC Pathways: Pyrimidine metabolism

Essentiality: Griffin Essential: 0.15 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2793c

Tuberculist Genomic Region

Rv2794c 4'-phosphopantetheinyl transferase EntD (EC 2.7.8.-)

Details for Rv2794c - 4'-phosphopantetheinyl transferase EntD (EC 2.7.8.-)

GO Terms: GO:0005515, GO:0005886, GO:0008897, GO:0019290

PATRIC Pathways: Phosphonate and phosphinate metabolism, Sphingolipid metabolism, Pantothenate and CoA biosynthesis, High-mannose type N-glycan biosynthesis, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2794c

Tuberculist Genomic Region

Rv2845c Prolyl-tRNA synthetase (EC 6.1.1.15)

Details for Rv2845c - Prolyl-tRNA synthetase (EC 6.1.1.15)

GO Terms: GO:0004827, GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.14 | In vivo Essential: 0.32

Go to Gene Page: Rv2845c

Tuberculist Genomic Region

Rv3011c Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7)

Details for Rv3011c - Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7)

GO Terms: GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis, Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv3011c

Tuberculist Genomic Region

Rv3141 PROBABLE NADPH QUINONE OXIDOREDUCTASE FADB4 (NADPH:QUINONE REDUCTASE) (ZETA-CRYSTALLIN) (EC 1.6.5.5)

Details for Rv3141 - PROBABLE NADPH QUINONE OXIDOREDUCTASE FADB4 (NADPH:QUINONE REDUCTASE) (ZETA-CRYSTALLIN) (EC 1.6.5.5)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3141

Tuberculist Genomic Region

Rv3631 Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster

Details for Rv3631 - Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster

GO Terms: NA

PATRIC Pathways: N-Glycan biosynthesis

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: 0.28

Go to Gene Page: Rv3631

Tuberculist Genomic Region

Rv3647c

Details for Rv3647c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3647c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 6.7e-23 e-value: 0.00000000000039
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006633 | GO:0072330 fatty acid biosynthetic process | monocarboxylic acid biosynthetic process
Displaying 1 - 19 of 19
GO:0047372 |

acylglycerol lipase activity

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0004622 |

lysophospholipase activity

GO:0008666 |

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity

GO:0000287 |

magnesium ion binding

GO:0031402 |

sodium ion binding

GO:0040007 |

growth

GO:0050662 |

coenzyme binding

GO:0051260 |

protein homooligomerization

GO:0070207 |

protein homotrimerization

GO:0003677 |

DNA binding

GO:0005829 |

cytosol

GO:0004158 |

dihydroorotate oxidase activity

GO:0005515 |

protein binding

GO:0008897 |

holo-[acyl-carrier-protein] synthase activity

GO:0019290 |

siderophore biosynthetic process

GO:0004827 |

proline-tRNA ligase activity