Organism : Clostridium acetobutylicum | Module List :
Galactose mutarotase related enzyme (NCBI ptt file)
Functional Annotations (4)
|Galactose mutarotase and related enzymes||cog/ cog|
|carbohydrate metabolic process||go/ biological_process|
|isomerase activity||go/ molecular_function|
|carbohydrate binding||go/ molecular_function|
Regulation information for CAC0697(Mouseover regulator name to see its description)
Motif information (de novo identified motifs for modules)
There are 4 motifs predicted.
|Motif Id||e-value||Consensus||Motif Logo|
Functional Enrichment for CAC0697
Module neighborhood information for CAC0697
|Gene||Common Name||Description||Module membership|
|CAC0155||MtlR||Putative regulator of the PTS system for mannitol (gene MltR) (NCBI ptt file)||170, 342|
|CAC0156||MltF||PTS system, mannitol-specific IIA domain (Ntr-type) (gene MltF) (NCBI ptt file)||170, 342|
|CAC0157||MtlD||Possible sigma factor, diverged member of sigF/sigE/sigG family (NCBI ptt file)||170, 342|
|CAC0263||serB||Phosphoserine phosphatase related protein (NCBI ptt file)||4, 218|
|CAC0309||CAC0309||Cell wall-associated hydrolase (NCBI ptt file)||4, 86|
|CAC0312||CAC0312||Hypothetical protein (NCBI ptt file)||4, 172|
|CAC0313||CAC0313||Phage shock protein A (NCBI ptt file)||4, 172|
|CAC0356||CAC0356||Similar to hypothetical protein [Thermotoga maritima] (NCBI ptt file)||170, 361|
|CAC0359||CAC0359||Similar to yteR (Bacilus subtilis) (NCBI ptt file)||170, 338|
|CAC0538||CAC0538||Beta-mannanase ManB-like enzyme, contains ChW-repeats (NCBI ptt file)||4, 205|
|CAC0694||CAC0694||Permease of the Na+: galactoside symporter family (NCBI ptt file)||170, 219|
|CAC0695||CAC0695||Altronate oxidoreductase (NCBI ptt file)||170, 301|
|CAC0696||CAC0696||Putative altronate dehydratase (NCBI ptt file)||170, 366|
|CAC0697||CAC0697||Galactose mutarotase related enzyme (NCBI ptt file)||4, 170|
|CAC0706||CAC0706||Endo-1,4-beta glucanase (fused to two ricin-B-like domains) (NCBI ptt file)||170, 251|
|CAC0707||rpoN||RNA polymerase sigma-54 factor (NCBI ptt file)||170, 272|
|CAC0722||CAC0722||Predicted membrane protein; CF-9 family (NCBI ptt file)||4, 309|
|CAC1048||CAC1048||Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily (NCBI ptt file)||4, 253|
|CAC1080||CAC1080||Uncharacterized protein, probably surface-located (NCBI ptt file)||170, 340|
|CAC1139||CAC1139||Phage related protein, YonO B.subtilis homolog (NCBI ptt file)||4, 16|
|CAC1165||CAC1165||Hypothetical protein (NCBI ptt file)||4, 104|
|CAC1184||CAC1184||Hypothetical protein (NCBI ptt file)||4, 16|
|CAC1215||CAC1215||Hypothetical protein (NCBI ptt file)||4, 176|
|CAC1319||glpF||Glycerol uptake facilitator protein, GLPF (NCBI ptt file)||4, 133|
|CAC1320||glpP||Glycerol-3-phosphate responsive antiterminator (mRNA-binding), GLPP (NCBI ptt file)||4, 86|
|CAC1345||xylT||D-xylose-proton symporter (NCBI ptt file)||170, 284|
|CAC1464||CAC1464||UVRA-like protein, probably involved in MDR transport (NCBI ptt file)||4, 166|
|CAC1529||CAC1529||Beta-xylosidase, family 43 glycosyl hydrolase (NCBI ptt file)||169, 170|
|CAC1606||CAC1606||Uncharacterized conserved protein (NCBI ptt file)||4, 73|
|CAC1607||CAC1607||Hypothetical protein (NCBI ptt file)||4, 137|
|CAC2050||CAC2050||Predicted membrane protein (NCBI ptt file)||4, 110|
|CAC2257||CAC2257||Hypothetical protein (NCBI ptt file)||4, 69|
|CAC2322||CAC2322||Hypothetical protein (NCBI ptt file)||4, 351|
|CAC2504||CAC2504||Hypothetical protein (NCBI ptt file)||4, 53|
|CAC2570||ganA||Predicted arabinogalactan endo-1,4-beta-galactosidase (NCBI ptt file)||75, 170|
|CAC2689||CAC2689||Uncharacterized protein, YJCM B.subtilis ortholog (NCBI ptt file)||4, 216|
|CAC2956||CAC2956||PTS system enzyme IIC component (galactitol/fructose specific) (NCBI ptt file)||136, 170|
|CAC2957||CAC2957||PTS system IIB component (galactitol/fructose specific) (NCBI ptt file)||136, 170|
|CAC2960||GalE||UDP-galactose 4-epimerase (NCBI ptt file)||75, 170|
|CAC2966||lacR||Lactose phosphotransferase system repressor lacR (NCBI ptt file)||170, 288|
|CAC2992||CAC2992||Predicted short-chain dehydrogenase (NCBI ptt file)||4, 132|
|CAC3087||CAC3087||Phosphoenolpyruvate-protein kinase (PTS system enzyme I) (NCBI ptt file)||4, 255|
|CAC3264||CAC3264||Uncharacterized conserved protein, YTFJ B.subtilis ortholog (NCBI ptt file)||4, 341|
|CAC3280||CAC3280||Possible surface protein, responsible for cell interaction; contains cell adhesion domain and ChW-repeats (NCBI ptt file)||4, 86|
|CAC3341||CAC3341||Multimeric flavodoxin WrbA family protein (NCBI ptt file)||4, 341|
|CAC3346||CAC3346||MDR-type permease (NCBI ptt file)||4, 150|
|CAC3425||glvC||PTS system, (possibly glucose-specific) IIBC component (NCBI ptt file)||133, 170|
|CAC3426||glvG||6-phospho-alpha-glucosidase (NCBI ptt file)||170, 284|
|CAC3430||CAC3430||Membrane associated, signal transduction histidine kinase-like ATPase (NCBI ptt file)||4, 353|
|CAC3451||CAC3451||Sugar/Na+(H+) simporter (NCBI ptt file)||170, 301|
|CAC3452||xynD||Beta-xylosidase, family 43 glycosyl hydrolase (NCBI ptt file)||142, 170|
|CAC3548||CAC3548||Uncharacterized conserved Zn-finger containing protein (NCBI ptt file)||4, 244|
|CAC3597||CAC3597||Rubrerythrin (NCBI ptt file)||4, 57|
|CAC3598||CAC3598||Rubrerythrin (NCBI ptt file)||4, 57|
|CAC3599||CAC3599||Hypothetical protein (NCBI ptt file)||4, 206|
|CAC3623||CAC3623||Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) (NCBI ptt file)||4, 30|
Gene Page Help
If the gene is associated with a module(s), its connection to given modules along with other members of that module are shown as network by using CytoscapeWeb. In this view, each green colored circular nodes represent module member genes, purple colored diamonds represent module motifs and red triangles represent regulators. Each node is connected to module (Bicluster) via edges. This representation provides quick overview of all genes, regulators and motifs for modules. It also allows one to see shared genes/motifs/regulators among diferent modules.
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Identification of functional enrichment for the module members is important in associating predicted motifs and regulatory influences with pathways. As described above, the network inference pipeline includes a functional enrichment module by which hypergeometric p-values are used to identify over representation of functional ontology terms among module members.
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Module Members Tab
Identity of gene members in a module may help to identify potential interactions between different functional modules. Therefore, neighbor genes that share the same module(s) with gene under consideration are shown here. For each memebr, gene name, description and modules that contain it are listed.
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CircVisOur circular module explorer is adapted from visquick originally developed by Dick Kreisberg of Ilya Shmulevich lab at ISB for The Cancer Genome Atlas. We use simplified version of visquick to display distribution of module members and their interactions across the genome. This view provides summary of regulation information for a gene. The main components are;
- 1. All genomic elements for the organism are represented as a circle and each element is separated by black tick marks. In this example chromosome and pDV represent main chromosome and plasmid for D. vulgaris Hildenborough, respectively.
- 2. Source gene
- 3. Target genes (other module members)
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- 5. Module(s) that source gene and target genes belong to
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