Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 171 - 180 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

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Title Gene Count Motif 1 e-value Motif 2 e-value Residual Expression TF Influences
Module_52 14
  • CD630_t0230 - tRNA-Asn Type: Gene
    Product: | Pathway: | COG:
  • CD630_15570 - Type: Gene
    Product:Putative peptidylprolyl isomerase | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_15600 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_15560 - Type: Gene
    Product:Putative polysaccharide deacetylase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_15590 - rsiV Type: Gene
    Product:Anti Sigma Factor, ECF family | Pathway: | COG: Function unknown
  • CD630_30550 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_20101 - ermC Type: Gene
    Product:23S rRNA methylase leader peptide | Pathway: | COG:
  • CD630_12040 - xseB Type: Gene
    Product:Exodeoxyribonuclease VII small subunit | Pathway: | COG: Replication, recombination and repair
  • CD630_11240 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_15580 - sigV Type: Gene
    Product:Extra-Cytoplasmic Function sigma factors, ECFfamily | Pathway: | COG: Transcription
  • CD630_17620 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_15620 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_30560 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_06700 - Type: Gene
    Product:Transcriptional regulator, beta-lactamsrepressor | Pathway: | COG: Transcription
0.54 NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_06700 - Type: Gene
    Product:Transcriptional regulator, beta-lactamsrepressor | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_397 27
  • CD630_10660 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03040 - Type: Gene
    Product:Conserved hypothetical protein, DUF1355 family | Pathway: | COG: Function unknown
  • CD630_35190 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_07610 - Type: Gene
    Product:Putative ATP-dependent RNA helicase | Pathway: | COG: Replication, recombination and repair
  • CD630_31840 - dpaL Type: Gene
    Product:Diaminopropionate ammonia-lyase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_34620 - Type: Gene
    Product:Putative antitoxin EndoAI | Pathway: | COG: Transcription
  • CD630_01200 - glmS Type: Gene
    Product:Glucosamine--fructose-6-phosphateaminotransferase [isomerizing] | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_34640 - GerS Type: Gene
    Product:Lipoprotein regulator, germination | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_34660 - acpS Type: Gene
    Product:Holo-[acyl-carrier-protein] synthase | Pathway: | COG: Lipid transport and metabolism
  • CD630_03110 - GerG Type: Gene
    Product:Germination regulator | Pathway: | COG:
  • CD630_10650 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03030 - argE Type: Gene
    Product:Acetylornithine deacetylase ArgE | Pathway: | COG: Amino acid transport and metabolism
  • CD630_06600 - tcdB Type: Gene
    Product:Toxin B | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_35200 - Type: Gene
    Product:Putative cation efflux protein | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_31790 - pyrD Type: Gene
    Product:Dihydroorotate dehydrogenase, catalytic subunit | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_07600 - Type: Gene
    Product:Putative Ca2+/Na+ antiporter | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_34630 - alr2 Type: Gene
    Product:Alanine racemase 2 | Pathway: Amino-acid biosynthesis | COG: Cell wall/membrane/envelope biogenesis
  • CD630_25621 - rpmB Type: Gene
    Product:50S ribosomal protein L28 | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_31830 - Type: Gene
    Product:Putative peptidase, M20 family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_34610 - EndoA Type: Gene
    Product:Endoribonuclease toxin | Pathway: | COG: Signal transduction mechanisms
  • CD630_31810 - Type: Gene
    Product:Putative amidohydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_03320 - bclA1 Type: Gene
    Product:Exosporium glycoprotein | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport, Extracellular structures
  • CD630_34650 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
0.00046 0.02 0.49 Inferelator: 2
Hypergeometric: 2

TF Influences from Inferelator

  1. CD630_06290 - Type: Gene
    Product:Transcriptional regulator, Crp family | Pathway: | COG: Transcription
  2. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12140 - spo0A Type: Gene
    Product:Stage 0 sporulation protein A | Pathway: | COG: Signal transduction mechanisms
  2. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription
Module_265 5
  • CD630_22600 - Type: Gene
    Product:Transporter, Major Facilitator Superfamily (MFS) | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24220 - Type: Gene
    Product:Sodium:alanine symporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_12600 - brnQ-2 Type: Gene
    Product:Branched chain amino acid transport systemcarrier protein | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24210 - Type: Gene
    Product:Putative amidohydrolase, M20D family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_31690 - Type: Gene
    Product:Putative malate transporter | Pathway: | COG: Function unknown
3.1 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_10230 - Type: Gene
    Product:Putative transcriptional regulator, HTH | Pathway: | COG: Transcription
  2. CD630_15580 - sigV Type: Gene
    Product:Extra-Cytoplasmic Function sigma factors, ECFfamily | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_201 23
  • CD630_24870 - Type: Gene
    Product:PTS system, fructose-like IIB component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30600 - Type: Gene
    Product:Phospho-alpha-glucosidase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25110 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_24650 - Type: Gene
    Product:Putative amino acid/polyamine transporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24850 - Type: Gene
    Product:Putative Xaa-Pro aminopeptidase, M24 family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_03900 - bglG Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_25090 - Type: Gene
    Product:Putative glycoside hydrolase, family 4 | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_05070 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf13 | Pathway: | COG: Function unknown
  • CD630_24890 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_30580 - Type: Gene
    Product:PTS system, alpha-glucoside-specific IIAcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03880 - bglF Type: Gene
    Product:PTS system, beta-glucoside-specific IIABCcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25100 - Type: Gene
    Product:PTS system, glucose-like IIBC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25120 - Type: Gene
    Product:PTS system, glucose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_24860 - Type: Gene
    Product:PTS system, fructose-like IIC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_23280 - Type: Gene
    Product:Sigma-54 dpendent regulator, PTS fructose family | Pathway: | COG: Signal transduction mechanisms
  • CD630_24840 - Type: Gene
    Product:Putative pyridoxal phosphate-dependenttransferase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_25080 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_05060 - Type: Gene
    Product:Reverse transcriptase/maturase/endonuclease,Group II intron | Pathway: | COG: Replication, recombination and repair
  • CD630_24880 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30590 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_03890 - bglA Type: Gene
    Product:6-phospho-beta-glucosidase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25070 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_30570 - Type: Gene
    Product:Transporter, Major Facilitator Superfamily (MFS) | Pathway: | COG: Carbohydrate transport and metabolism
0 NA 0.49 Inferelator: 1
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_25080 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12750 - codY Type: Gene
    Product:Transcriptional regulator, GTP-sensingpleiotropic repressor | Pathway: | COG: Transcription
Module_134 19
  • CD630_31320 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03350 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_36300 - Type: Gene
    Product:PTS system, fructose/mannitol-family IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03370 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_36260 - Type: Gene
    Product:Putative 4-hydroxy-2-oxoglutarate aldolase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25520 - Type: Gene
    Product:Putative phosphosugar isomerase | Pathway: | COG: Function unknown
  • CD630_17350 - Type: Gene
    Product:Putative hydrolase | Pathway: | COG: Function unknown
  • CD630_36310 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_31310 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_17370 - Type: Gene
    Product:Putative divalent ion symporter | Pathway: | COG: Amino acid transport and metabolism, Carbohydrate transport and metabolism
  • CD630_25530 - Type: Gene
    Product:PTS system, fructose/mannitol-family IICcomponent (Disrupted IStron) | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17360 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_03380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_25510 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_31330 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_17380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_03360 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_17390 - Type: Gene
    Product:Two-component response regulator, sigma-54dependent regulator | Pathway: | COG: Signal transduction mechanisms
0.000017 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  2. CD630_30770 - Type: Gene
    Product:Transcriptional regulator, RpiR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_87 7
  • CD630_35871 - Type: Gene
    Product:Fragment of putative transposase (N-terminalregion) | Pathway: | COG:
  • CD630_35940 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Energy production and conversion
  • CD630_00030 - Type: Gene
    Product:Putative RNA-binding mediating protein | Pathway: | COG: Function unknown
  • CD630_20990 - XdhD Type: Gene
    Product:Xanthine dehydrogenase subunit XdhD,molybdopterin-binding | Pathway: | COG: Energy production and conversion
  • CD630_35930 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_21010 - xdhB Type: Gene
    Product:Xanthine dehydrogenase subunit XdhB, FAD-binding | Pathway: | COG: Energy production and conversion
  • CD630_21000 - XdhC3 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC3 | Pathway: | COG: Energy production and conversion
NA NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_06480 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
  2. CD630_35830 - Type: Gene
    Product:Transcriptional regulator, MerR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_218 19
  • CD630_04351 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn2-Orf32 | Pathway: | COG:
  • CD630_04360 - Type: Gene
    Product:Putative recombinase Tn1549-like, CTn2-Orf34 | Pathway: | COG: Replication, recombination and repair
  • CD630_21140 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_33722 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn7-Orf6 | Pathway: | COG: Function unknown
  • CD630_21130 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
NA NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_21140 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_40 19
  • CD630_11041 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf18 | Pathway: | COG: Function unknown
  • CD630_11042 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf17 | Pathway: | COG: Function unknown
  • CD630_11050 - Type: Gene
    Product:Putative antirestriction protein Tn1549-like,CTn4-Orf16 | Pathway: | COG: Function unknown
  • CD630_11071 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf12 | Pathway: | COG: Function unknown
  • CD630_11070 - Type: Gene
    Product:Putative cell surface protein Tn1549-like,CTn4-Orf13 | Pathway: | COG: Function unknown
  • CD630_11061 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf14 | Pathway: | COG: Function unknown
  • CD630_33400 - Type: Gene
    Product:Putative antirestriction protein Tn916-like,CTn6-Orf17 | Pathway: | COG: Function unknown
  • CD630_33360 - Type: Gene
    Product:Putative cell wall hydrolase Tn916-like,CTn6-Orf13 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_33280 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf4 | Pathway: | COG: Function unknown
  • CD630_11120 - Type: Gene
    Product:Putative membrane protein Tn1549-like, CTn4-Orf7 | Pathway: | COG: Function unknown
  • CD630_11080 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf11 | Pathway: | COG: Function unknown
  • CD630_33370 - Type: Gene
    Product:Putative membrane protein Tn916-like, CTn6-Orf14 | Pathway: | COG: Function unknown
  • CD630_11090 - Type: Gene
    Product:DNA-methyltransferase, cytosine-N4-specific;Tn1549-like, CTn4-Orf10 | Pathway: | COG: Replication, recombination and repair
  • CD630_33390 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf16 | Pathway: | COG: Function unknown
  • CD630_11060 - topB Type: Gene
    Product:DNA topoisomerase III; Tn1549-like, CTn4-Orf15 | Pathway: | COG: Replication, recombination and repair
  • CD630_33380 - Type: Gene
    Product:Putative ATPase Tn916-like, CTn6-Orf15 | Pathway: | COG: Function unknown
  • CD630_33350 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf12 | Pathway: | COG: Function unknown
  • CD630_11110 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf8 | Pathway: | COG: Function unknown
  • CD630_11100 - Type: Gene
    Product:Putative hydrolase Tn1549-like, CTn4-Orf9 | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport
0.00028 2.7 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_01710 - rex Type: Gene
    Product:Transcriptional regulator, Redox-sensingrepressor Rex | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_269 20
  • CD630_14090 - Type: Gene
    Product:Putative competence-damage inducible protein,CinA family | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_08760 - Type: Gene
    Product:ABC-type transport system, sugar-familyextracellular solute-binding protein | Pathway: | COG: Function unknown
  • CD630_14080 - ddl Type: Gene
    Product:D-alanine--D-alanine ligase (D-alanylalaninesynthetase) (D-Ala-D-Ala ligase) | Pathway: Cell wall biogenesis | COG: Cell wall/membrane/envelope biogenesis
  • CD630_14100 - Type: Gene
    Product:Putative hydrolase, HAD superfamily, subfamilyIIB | Pathway: | COG: Function unknown
  • CD630_02170 - Type: Gene
    Product:Putative nitroreductase | Pathway: | COG: Energy production and conversion
  • CD630_08750 - Type: Gene
    Product:ABC-type transport system, sugar-family permease | Pathway: | COG: Function unknown
  • CD630_08730 - Type: Gene
    Product:ABC-type transport system sugar-familyextracellular solute-binding lipoprotein | Pathway: | COG: Function unknown
  • CD630_10140 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_14070 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
  • CD630_08770 - Type: Gene
    Product:ABC-type transport system, sugar-familyATP-binding protein | Pathway: | COG: Function unknown
  • CD630_19550 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_14060 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_14050 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Function unknown
  • CD630_08740 - Type: Gene
    Product:ABC-type transport system, sugar-familyATP-binding protein | Pathway: | COG: Function unknown
  • CD630_10130 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_19570 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_08780 - Type: Gene
    Product:ABC-type transport system, sugar-specificpermease | Pathway: | COG: Function unknown
  • CD630_19560 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_17590 - Type: Gene
    Product:Putative SAM-dependent methyltransferase | Pathway: | COG: Function unknown
  • CD630_19540 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
0.0000057 0 0.49 Inferelator: 3
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_11770 - fapR Type: Gene
    Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) | Pathway: | COG: Transcription
  2. CD630_19100 - eutV Type: Gene
    Product:Two-component response regulator, Ethanolaminespecific | Pathway: | COG: Signal transduction mechanisms
  3. CD630_26650 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12750 - codY Type: Gene
    Product:Transcriptional regulator, GTP-sensingpleiotropic repressor | Pathway: | COG: Transcription
Module_354 10
  • CD630_05250 - Type: Gene
    Product:Fragment of aminobenzoyl-glutamate transporter(Part 2) | Pathway: | COG: Coenzyme transport and metabolism, Coenzyme transport and metabolism
  • CD630_02760 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_11860 - Type: Gene
    Product:Transcriptional regulator, sigma-54-dependent | Pathway: | COG: Transcription
  • CD630_33680 - Type: Gene
    Product:Putative ribosome biogenesis GTPase RsgA;putative EngC-like GTPase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30040 - kdgT2 Type: Gene
    Product:2-keto-3-deoxygluconate permease 2 | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_06450 - Type: Gene
    Product:ABC-type transport system,lantibiotic/multidrug-family ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_30030 - Type: Gene
    Product:Putative N-terminus region of carbohydratehydrolase, SAF domain | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_01111 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_05081 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf6 | Pathway: | COG: Function unknown
  • CD630_33681 - Type: Gene
    Product:Putative zinc finger protein | Pathway: | COG: Function unknown
0.55 NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_03200 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test