Module 167 Residual: 0.51

Title Bicluster Model Residual Score
bicluster_0167 v02 0.51 -8.58
Displaying 1 - 17 of 17
Rv0158 Transcriptional regulator, TetR family

Details for Rv0158 - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0158

Tuberculist Genomic Region

Rv0330c Transcriptional regulator, TetR family

Details for Rv0330c - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0330c

Tuberculist Genomic Region

Rv0474 \Transcriptional regulator, XRE family\\\""

Details for Rv0474 - \Transcriptional regulator, XRE family\\\""

GO Terms: GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0474

Tuberculist Genomic Region

Rv0475 Iron-regulated heparin binding hemagglutinin HbhA (Adhesin)

Details for Rv0475 - Iron-regulated heparin binding hemagglutinin HbhA (Adhesin)

GO Terms: GO:0005515, GO:0005618, GO:0005829, GO:0005886, GO:0007157, GO:0008201, GO:0009986, GO:0042803, GO:0044078

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0475

Tuberculist Genomic Region

Rv0711 Arylsulfatase (EC 3.1.6.1)

Details for Rv0711 - Arylsulfatase (EC 3.1.6.1)

GO Terms: GO:0005886, GO:0010033

PATRIC Pathways: C21-Steroid hormone metabolism, Sphingolipid metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0711

Tuberculist Genomic Region

Rv0735 RNA polymerase sigma-70 factor

Details for Rv0735 - RNA polymerase sigma-70 factor

GO Terms: GO:0005515, GO:0006355

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0735

Tuberculist Genomic Region

Rv0736 Possible membrane protein

Details for Rv0736 - Possible membrane protein

GO Terms: GO:0005515, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv0736

Tuberculist Genomic Region

Rv1169c (MTV005.05c), len: 100. similar to the N-terminal region of the M. tuberculosis PE family of proteinseg. TR:O05297 (EMBL:Z93777) MTCI364.07 (99 aa), fasta scores; opt: 209 z-score: 407.6 E(): 1.6e-15, 37.4% identityin 99 aa overlap. Also simlar to the N-terminus of M. tuberculosis TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa), fasta scores; opt: 193z-score: 381.8 E(): 4.4e-14, 37.2% identity in 94 aa overlap. Contains a helix-turn-heix motiffrom aa 88-109(+2.76 SD)

Details for Rv1169c - (MTV005.05c), len: 100. similar to the N-terminal region of the M. tuberculosis PE family of proteinseg. TR:O05297 (EMBL:Z93777) MTCI364.07 (99 aa), fasta scores; opt: 209 z-score: 407.6 E(): 1.6e-15, 37.4% identityin 99 aa overlap. Also simlar to the N-terminus of M. tuberculosis TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa), fasta scores; opt: 193z-score: 381.8 E(): 4.4e-14, 37.2% identity in 94 aa overlap. Contains a helix-turn-heix motiffrom aa 88-109(+2.76 SD)

GO Terms: GO:0004806, GO:0040007, GO:0052572

PATRIC Pathways: Glycerolipid metabolism

Essentiality: Griffin Essential: 0.63 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv1169c

Tuberculist Genomic Region

Rv1532c Putative uncharacterized protein BCG_1584c

Details for Rv1532c - Putative uncharacterized protein BCG_1584c

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1532c

Tuberculist Genomic Region

Rv3863 Probable forkhead-associated protein

Details for Rv3863 - Probable forkhead-associated protein

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3863

Tuberculist Genomic Region

Rv0068 Oxidoreductase/Short-chain dehydrogenase

Details for Rv0068 - Oxidoreductase/Short-chain dehydrogenase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0068

Tuberculist Genomic Region

Rv0712 Sulfatase modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1)

Details for Rv0712 - Sulfatase modifying factor 1 precursor (C-alpha-formyglycine- generating enzyme 1)

GO Terms: GO:0018083

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0712

Tuberculist Genomic Region

Rv3061c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv3061c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0005618

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv3061c

Tuberculist Genomic Region

Rv3249c Transcriptional regulator, TetR family

Details for Rv3249c - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3249c

Tuberculist Genomic Region

Rv3250c Rubredoxin

Details for Rv3250c - Rubredoxin

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3250c

Tuberculist Genomic Region

Rv3251c Rubredoxin

Details for Rv3251c - Rubredoxin

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3251c

Tuberculist Genomic Region

Rv3252c Alkane-1 monooxygenase (EC 1.14.15.3)

Details for Rv3252c - Alkane-1 monooxygenase (EC 1.14.15.3)

GO Terms: GO:0018685, GO:0080133

PATRIC Pathways: Retinol metabolism, Arachidonic acid metabolism, Fatty acid metabolism

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3252c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0021 e-value: 49
Displaying 1 - 1 of 1
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 18 of 18
GO:0005829 |

cytosol

GO:0005515 |

protein binding

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0007157 |

heterophilic cell-cell adhesion

GO:0008201 |

heparin binding

GO:0009986 |

cell surface

GO:0042803 |

protein homodimerization activity

GO:0044078 |

positive regulation by symbiont of host receptor-mediated endocytosis

GO:0010033 |

response to organic substance

GO:0006355 |

regulation of transcription, DNA-dependent

GO:0040007 |

growth

GO:0004806 |

triglyceride lipase activity

GO:0052572 |

response to host immune response

GO:0018083 |

peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine

GO:0018685 |

alkane 1-monooxygenase activity

GO:0080133 |

midchain alkane hydroxylase activity