Module 244 Residual: 0.55

Title Bicluster Model Residual Score
bicluster_0244 v02 0.55 -19.58
Displaying 1 - 17 of 17
Rv1182 POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2

Details for Rv1182 - POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: 0.20 | In vivo Essential: NA

Go to Gene Page: Rv1182

Tuberculist Genomic Region

Rv1183 membrane protein, MmpL family, putative

Details for Rv1183 - membrane protein, MmpL family, putative

GO Terms: GO:0005576, GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.10 | In vitro Essential: NA | In vivo Essential: 0.06

Go to Gene Page: Rv1183

Tuberculist Genomic Region

Rv2124c 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Details for Rv2124c - 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

GO Terms: GO:0008705, GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Cysteine and methionine metabolism, Selenoamino acid metabolism, One carbon pool by folate

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2124c

Tuberculist Genomic Region

Rv2409c Protein containing transglutaminase-like domain, putative cysteine protease

Details for Rv2409c - Protein containing transglutaminase-like domain, putative cysteine protease

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2409c

Tuberculist Genomic Region

Rv2410c Protein containing domains DUF403

Details for Rv2410c - Protein containing domains DUF403

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2410c

Tuberculist Genomic Region

Rv2411c Protein containing domains DUF404, DUF407

Details for Rv2411c - Protein containing domains DUF404, DUF407

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2411c

Tuberculist Genomic Region

Rv3207c

Details for Rv3207c -

GO Terms: GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.25 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3207c

Tuberculist Genomic Region

Rv3528c

Details for Rv3528c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3528c

Tuberculist Genomic Region

Rv3767c O-Methyltransferase involved in polyketide biosynthesis

Details for Rv3767c - O-Methyltransferase involved in polyketide biosynthesis

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3767c

Tuberculist Genomic Region

Rv3822 PE family protein

Details for Rv3822 - PE family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3822

Tuberculist Genomic Region

Rv1184c POSSIBLE EXPORTED PROTEIN

Details for Rv1184c - POSSIBLE EXPORTED PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: 0.36

Go to Gene Page: Rv1184c

Tuberculist Genomic Region

Rv1185c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv1185c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: 0.35

Go to Gene Page: Rv1185c

Tuberculist Genomic Region

Rv2412 SSU ribosomal protein S20p

Details for Rv2412 - SSU ribosomal protein S20p

GO Terms: GO:0006412, GO:0003723, GO:0005622, GO:0003735, GO:0005840, GO:0005829, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv2412

Tuberculist Genomic Region

Rv2808

Details for Rv2808 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: 0.24

Go to Gene Page: Rv2808

Tuberculist Genomic Region

Rv3208 Transcriptional regulator, TetR family

Details for Rv3208 - Transcriptional regulator, TetR family

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3208

Tuberculist Genomic Region

Rv3768

Details for Rv3768 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3768

Tuberculist Genomic Region

Rv3824c Polyketide synthase associated protein PapA1

Details for Rv3824c - Polyketide synthase associated protein PapA1

GO Terms: GO:0008415, GO:0046506

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3824c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00000047 e-value: 0.00000089
Displaying 1 - 1 of 1
Transcriptional regulator, TetR family
regulates 12 modules
Weight: 
0.23
up-regulates
ESX-1 secreted protein regulator EspR
regulates 8 modules
Weight: 
0.17
up-regulates
Sporulation regulatory protein WhiD
regulates 6 modules
Weight: 
0.15
up-regulates
transcriptional regulator, AfsR/DnrI/RedD family
regulates 14 modules
Weight: 
0.12
up-regulates
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
regulates 28 modules
Weight: 
0.12
up-regulates
regulates 2 modules
Weight: 
0.11
up-regulates
regulates 5 modules
Weight: 
0.11
up-regulates
Transcriptional regulator, TetR family
regulates 1 modules
Weight: 
-0.09
down-regulates
Transcriptional regulator, TetR family
regulates 2 modules
Weight: 
-0.09
down-regulates
Transcriptional regulator, TetR family
regulates 23 modules
Weight: 
0.09
up-regulates
Histone protein Lsr2
regulates 12 modules
Weight: 
-0.09
down-regulates
regulates 13 modules
Weight: 
-0.09
down-regulates
Phosphate transport system regulatory protein PhoU
regulates 11 modules
Weight: 
0.07
up-regulates
HTH-type transcriptional regulator BetI
regulates 16 modules
Weight: 
-0.07
down-regulates
regulates 3 modules
Weight: 
0.07
up-regulates
Transcriptional regulator, TetR family
regulates 5 modules
Weight: 
-0.07
down-regulates
Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein
regulates 38 modules
Weight: 
0.06
up-regulates
regulates 23 modules
Weight: 
-0.06
down-regulates
Phosphate transport system regulatory protein PhoU
regulates 14 modules
Weight: 
0.05
up-regulates
Transcriptional regulator, ArsR family
regulates 25 modules
Weight: 
-0.04
down-regulates
Transcriptional regulator WhiB-like WhiB6
regulates 10 modules
Weight: 
-0.03
down-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 14 of 14
GO:0040007 |

growth

GO:0005576 |

extracellular region

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0008705 |

methionine synthase activity

GO:0006412 |

translation

GO:0003723 |

RNA binding

GO:0005622 |

intracellular

GO:0003735 |

structural constituent of ribosome

GO:0005840 |

ribosome

GO:0008415 |

NA

GO:0046506 |

sulfolipid biosynthetic process