Module 560 Residual: 0.59

Title Bicluster Model Residual Score
bicluster_0560 v02 0.59 -9.14
Displaying 1 - 20 of 20
Rv2482c Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)

Details for Rv2482c - Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)

GO Terms: GO:0004366, GO:0005886

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.49 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2482c

Tuberculist Genomic Region

Rv2483c Phosphoserine phosphatase (EC 3.1.3.3) / 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv2483c - Phosphoserine phosphatase (EC 3.1.3.3) / 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0005886

PATRIC Pathways: Methane metabolism, Glycine, serine and threonine metabolism, Glycerophospholipid metabolism, Glycerolipid metabolism

Essentiality: Griffin Essential: 0.57 | In vitro Essential: NA | In vivo Essential: 0.31

Go to Gene Page: Rv2483c

Tuberculist Genomic Region

Rv2484c Acyltransferase, ws/dgat/mgat subfamily protein

Details for Rv2484c - Acyltransferase, ws/dgat/mgat subfamily protein

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2484c

Tuberculist Genomic Region

Rv0186 Beta-glucosidase (EC 3.2.1.21)

Details for Rv0186 - Beta-glucosidase (EC 3.2.1.21)

GO Terms: GO:0005886

PATRIC Pathways: Starch and sucrose metabolism, Phenylpropanoid biosynthesis, Cyanoamino acid metabolism

Essentiality: Griffin Essential: 0.13 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0186

Tuberculist Genomic Region

Rv0188 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Details for Rv0188 - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0188

Tuberculist Genomic Region

Rv0232 Transcriptional regulator, TetR family

Details for Rv0232 - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0232

Tuberculist Genomic Region

Rv0233 Ribonucleotide-diphosphate reductase subunit beta (EC 1.17.4.1)

Details for Rv0233 - Ribonucleotide-diphosphate reductase subunit beta (EC 1.17.4.1)

GO Terms: GO:0005829

PATRIC Pathways: Purine metabolism, Glutathione metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0233

Tuberculist Genomic Region

Rv0250c

Details for Rv0250c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0250c

Tuberculist Genomic Region

Rv0275c Transcriptional regulator, TetR family

Details for Rv0275c - Transcriptional regulator, TetR family

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0275c

Tuberculist Genomic Region

Rv0276

Details for Rv0276 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0276

Tuberculist Genomic Region

Rv0670 Endonuclease IV (EC 3.1.21.2)

Details for Rv0670 - Endonuclease IV (EC 3.1.21.2)

GO Terms: GO:0008833

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: 0.32

Go to Gene Page: Rv0670

Tuberculist Genomic Region

Rv1052

Details for Rv1052 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1052

Tuberculist Genomic Region

Rv1264 Adenylate cyclase (EC 4.6.1.1)

Details for Rv1264 - Adenylate cyclase (EC 4.6.1.1)

GO Terms: GO:0004016, GO:0004016, GO:0009268, GO:0030145, GO:0042803, GO:0009405

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1264

Tuberculist Genomic Region

Rv1316c Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)

Details for Rv1316c - Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)

GO Terms: GO:0003908, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.43 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1316c

Tuberculist Genomic Region

Rv1317c Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)

Details for Rv1317c - Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1317c

Tuberculist Genomic Region

Rv1454c Quinone oxidoreductase (EC 1.6.5.5)

Details for Rv1454c - Quinone oxidoreductase (EC 1.6.5.5)

GO Terms: GO:0005576, GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1454c

Tuberculist Genomic Region

Rv1996 Universal stress protein family

Details for Rv1996 - Universal stress protein family

GO Terms: GO:0005618, GO:0005886, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1996

Tuberculist Genomic Region

Rv2364c GTP-binding protein Era

Details for Rv2364c - GTP-binding protein Era

GO Terms: GO:0003676, GO:0005622, GO:0005525, GO:0005829, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2364c

Tuberculist Genomic Region

Rv2557

Details for Rv2557 -

GO Terms: GO:0009267, GO:0009405

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2557

Tuberculist Genomic Region

Rv3290c Probable L-lysine-epsilon aminotransferase (EC 2.6.1.36) (L-lysine aminotransferase) (Lysine 6-aminotransferase)

Details for Rv3290c - Probable L-lysine-epsilon aminotransferase (EC 2.6.1.36) (L-lysine aminotransferase) (Lysine 6-aminotransferase)

GO Terms: NA

PATRIC Pathways: Lysine biosynthesis

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3290c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.014 e-value: 21
Displaying 1 - 1 of 1
regulates 13 modules
Weight: 
0.34
up-regulates
regulates 52 modules
Weight: 
0.18
up-regulates
Transcriptional regulator, TetR family
regulates 8 modules
Weight: 
0.15
up-regulates
Transcriptional regulator, GntR family
regulates 22 modules
Weight: 
0.15
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0009396 | GO:0042559 | GO:0006732 | GO:0042398 folic acid-containing compound biosynthe... | pteridine-containing compound biosynthet... | coenzyme metabolic process | cellular modified amino acid biosyntheti...
Displaying 1 - 19 of 19
GO:0004366 |

glycerol-3-phosphate O-acyltransferase activity

GO:0005886 |

plasma membrane

GO:0005829 |

cytosol

GO:0008833 |

deoxyribonuclease IV (phage-T4-induced) activity

GO:0004016 |

adenylate cyclase activity

GO:0009268 |

response to pH

GO:0030145 |

manganese ion binding

GO:0042803 |

protein homodimerization activity

GO:0009405 |

pathogenesis

GO:0003908 |

methylated-DNA-[protein]-cysteine S-methyltransferase activity

GO:0005618 |

cell wall

GO:0005576 |

extracellular region

GO:0071500 |

cellular response to nitrosative stress

GO:0003676 |

nucleic acid binding

GO:0005622 |

intracellular

GO:0005525 |

GTP binding

GO:0040007 |

growth

GO:0009267 |

cellular response to starvation