Module 562 Residual: 0.57

Title Bicluster Model Residual Score
bicluster_0562 v02 0.57 -15.43
Displaying 1 - 14 of 14
Rv2096c FIG005453: Putative DeoR-family transcriptional regulator

Details for Rv2096c - FIG005453: Putative DeoR-family transcriptional regulator

GO Terms: GO:0005515, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2096c

Tuberculist Genomic Region

Rv2097c Pup ligase PafA, possible component of postulated heterodimer PafA-PafA'

Details for Rv2097c - Pup ligase PafA, possible component of postulated heterodimer PafA-PafA'

GO Terms: GO:0005515, GO:0005524, GO:0005618, GO:0005886, GO:0010498, GO:0016881, GO:0051409, GO:0070490

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2097c

Tuberculist Genomic Region

Rv2133c Phosphatidylinositol 3-and 4-kinase family protein

Details for Rv2133c - Phosphatidylinositol 3-and 4-kinase family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2133c

Tuberculist Genomic Region

Rv2134c

Details for Rv2134c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2134c

Tuberculist Genomic Region

Rv2135c Phosphoglycerate mutase family

Details for Rv2135c - Phosphoglycerate mutase family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2135c

Tuberculist Genomic Region

Rv3605c FIG027937: secreted protein

Details for Rv3605c - FIG027937: secreted protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3605c

Tuberculist Genomic Region

Rv3606c 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3)

Details for Rv3606c - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3)

GO Terms: GO:0003848

PATRIC Pathways: Folate biosynthesis

Essentiality: Griffin Essential: 0.11 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3606c

Tuberculist Genomic Region

Rv3607c Dihydroneopterin aldolase (EC 4.1.2.25)

Details for Rv3607c - Dihydroneopterin aldolase (EC 4.1.2.25)

GO Terms: GO:0004150, GO:0040007, GO:0051260

PATRIC Pathways: Folate biosynthesis

Essentiality: Griffin Essential: 0.05 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv3607c

Tuberculist Genomic Region

Rv3608c Dihydropteroate synthase (EC 2.5.1.15)

Details for Rv3608c - Dihydropteroate synthase (EC 2.5.1.15)

GO Terms: GO:0004156, GO:0004156, GO:0040007

PATRIC Pathways: Folate biosynthesis

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv3608c

Tuberculist Genomic Region

Rv3609c GTP cyclohydrolase I (EC 3.5.4.16) type 1

Details for Rv3609c - GTP cyclohydrolase I (EC 3.5.4.16) type 1

GO Terms: GO:0003934, GO:0040007

PATRIC Pathways: Folate biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.11 | In vivo Essential: NA

Go to Gene Page: Rv3609c

Tuberculist Genomic Region

Rv3610c Cell division protein FtsH (EC 3.4.24.-)

Details for Rv3610c - Cell division protein FtsH (EC 3.4.24.-)

GO Terms: GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0005829, GO:0005886, GO:0006508, GO:0030163, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv3610c

Tuberculist Genomic Region

Rv3625c tRNA(Ile)-lysidine synthetase

Details for Rv3625c - tRNA(Ile)-lysidine synthetase

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv3625c

Tuberculist Genomic Region

Rv3626c

Details for Rv3626c -

GO Terms: GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3626c

Tuberculist Genomic Region

Rv3627c D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)

Details for Rv3627c - D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4)

GO Terms: GO:0009002, GO:0005576, GO:0040007

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv3627c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 1500 e-value: 6400
Displaying 1 - 1 of 1
putative RNA polymerase sigma factor
regulates 5 modules
Weight: 
0.17
up-regulates
cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
regulates 28 modules
Weight: 
0.14
up-regulates
Arginine pathway regulatory protein ArgR, repressor of arg regulon
regulates 31 modules
Weight: 
0.13
up-regulates
regulates 9 modules
Weight: 
0.12
up-regulates
Transcriptional regulatory protein EmbR
regulates 2 modules
Weight: 
-0.12
down-regulates
Transcriptional regulatory protein
regulates 18 modules
Weight: 
0.12
up-regulates
Transcriptional regulator, TetR family
regulates 12 modules
Weight: 
0.11
up-regulates
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
0.10
up-regulates
regulates 2 modules
Weight: 
0.10
up-regulates
RNA polymerase sigma factor SigB
regulates 61 modules
Weight: 
0.08
up-regulates
tRNA dihydrouridine synthase B (EC 1.-.-.-)
regulates 4 modules
Weight: 
0.08
up-regulates
\Transcriptional regulator, TetR family\\\""
regulates 32 modules
Weight: 
0.07
up-regulates
COG0714: MoxR-like ATPases
regulates 31 modules
Weight: 
0.06
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 21 of 21
GO:0005515 |

protein binding

GO:0005886 |

plasma membrane

GO:0005524 |

ATP binding

GO:0005618 |

cell wall

GO:0010498 |

proteasomal protein catabolic process

GO:0016881 |

acid-amino acid ligase activity

GO:0051409 |

response to nitrosative stress

GO:0070490 |

protein pupylation

GO:0003848 |

2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity

GO:0004150 |

dihydroneopterin aldolase activity

GO:0040007 |

growth

GO:0051260 |

protein homooligomerization

GO:0004156 |

dihydropteroate synthase activity

GO:0003934 |

GTP cyclohydrolase I activity

GO:0008150 |

biological_process

GO:0005829 |

cytosol

GO:0006508 |

proteolysis

GO:0030163 |

protein catabolic process

GO:0009002 |

serine-type D-Ala-D-Ala carboxypeptidase activity

GO:0005576 |

extracellular region