Rv0135c Transcriptional regulator, TetR family

Rv0135c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0366 with residual 0.53 and bicluster_0567 with residual 0.48.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0366 and 200.00 and 6,500.00 for bicluster_0567 respectively.

These modules are enriched for following go terms: hydrolase activity, acting on ester bond... hydro-lyase activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 71 - 80 of 119
Gene Target Differential Expression Distance Expression pvalue Type
[Acyl-carrier-protein] acetyl transferase of FASI (EC 2.3.1.38) / Enoyl-[acyl-carrier-protein] reductase of FASI (EC 1.3.1.9) / 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase of FASI (EC 4.2.1.61) / [Acyl-carrier-protein] malonyl transferase of FASI (EC 2.3.1.39) / [Acyl-carrier-protein] palmitoyl transferase of FASI (EC 2.3.1.-) / Acyl carrier protein of FASI / 3-oxoacyl-[acyl-carrier-protein] reductase of FASI (EC 1.1.1.100) / 3-oxoacyl-[acyl-carrier-protein] synthase of FASI (EC 2.3.1.41)
No -138 0.27 0.693421 Primary.TSS
Possible membrane protein
No 41 0.2 0.643946 Primary.TSS
No -9 -0.69 0.286813 Primary.TSS
No -7 0.16 0.807045 Internal.TSS
No -16 0.16 0.807045 CDS
Possible membrane protein
No -77 0.54 0.0474212 Internal.TSS
Possible membrane protein
No -59 0.54 0.0474212 CDS
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8)
No -45 0.08 0.814608 Primary.TSS
1-deoxy-D-xylulose 5-phosphate reductoisomerase (EC 1.1.1.267)
No -51 -0.14 0.69741 Primary.TSS
Transcriptional regulatory protein glnR
Repressed -33 -2.64 0.00000000000000263 CDS
not assigned to any KEGG Pathway.
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.98 U
D3I 3 3 3.83 14.55 I
D3U 3 3 3.83 14.19 U
D5I 9 5 6.00 12.91 I
D5U 17 5 6.00 12.92 U
D7I 18 7 8.14 14.19 I
D7U 19 7 8.14 13.98 U
D14I 4 14 15.63 12.54 I
D14U 4 14 15.63 13.74 U
D17I 3 17 19.15 10.82 I
D17U 3 17 19.15 13.48 U
D21I 4 21 23.23 10.43 I
D21U 4 21 23.23 13.56 U
D24I 3 24 26.60 8.46 I
D24U 3 24 26.60 13.44 U
D28I 4 28 30.61 8.77 I
D28U 4 28 30.61 13.41 U