Rv0494 Lactate-responsive regulator LldR in Enterobacteria, GntR family

Rv0494 (Lactate-responsive regulator LldR in Enterobacteria, GntR family) is predicted to be co-regulated in modules bicluster_0160 with residual 0.59 and bicluster_0441 with residual 0.47.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 5,000.00 for bicluster_0160 and 75.00 and 120.00 for bicluster_0441 respectively.

These modules are enriched for following go terms: calcium- and calmodulin-responsive adeny..., adenylate cyclase activity, cyclase activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 25
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, TetR family
No -90 0.07 0.769972 CDS
Repressed -3 -1.41 0.000000000007 Primary.TSS
fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal:FAD dependent oxidoreductase
No -125 0.51 0.0346285 Antisense.TSS
No -119 0.38 0.0958695 Primary.TSS
Resuscitation-promoting factor RpfD
No -111 0.51 0.0131863 CDS
Ribokinase (EC 2.7.1.15)
No -122 0.42 0.151223 CDS
Induced 23 0.64 0.0064154 CDS
FIG019327: Probable conserved membrane protein
No -88 0.21 0.169116 CDS
Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase
No 68 0.7 0.127035 CDS
Pigment protein
Repressed 30 -2.73 0.000000145 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.80 U
D3I 3 3 3.83 12.00 I
D3U 3 3 3.83 11.73 U
D5I 9 5 6.00 12.69 I
D5U 17 5 6.00 12.13 U
D7I 18 7 8.14 13.41 I
D7U 19 7 8.14 12.10 U
D14I 4 14 15.63 12.76 I
D14U 4 14 15.63 11.29 U
D17I 3 17 19.15 13.16 I
D17U 3 17 19.15 11.06 U
D21I 4 21 23.23 13.64 I
D21U 4 21 23.23 11.63 U
D24I 3 24 26.60 13.94 I
D24U 3 24 26.60 11.40 U
D28I 4 28 30.61 14.14 I
D28U 4 28 30.61 11.89 U