Rv0576 Transcriptional regulator, ArsR family

Rv0576 (Transcriptional regulator, ArsR family) is predicted to be co-regulated in modules bicluster_0464 with residual 0.52 and bicluster_0530 with residual 0.56.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.03 and 2.20 for bicluster_0464 and 0.00 and 0.46 for bicluster_0530 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 34
Gene Target Differential Expression Distance Expression pvalue Type
Aldehyde dehydrogenase (EC 1.2.1.3)
Repressed -123 -0.85 0.00691037 CDS
Repressed -7 -1.53 0.00169671 Primary.TSS
Putative esterase
No -42 -0.51 0.0910738 Primary.TSS
Bacterioferritin (BFR)
No -117 -0.57 0.00258904 Primary.TSS
Transporter, LysE family
Repressed -4 -0.96 0.00305731 Primary.TSS
No results were found NA 24 Primary.TSS
Transcriptional regulator, ArsR family
Repressed -22 -2.91 0.000000000000197 CDS
FIG055075: Possibly a cell division protein, antigen 84 in Mycobacteria
No 58 0.03 0.887689 Primary.TSS
No -120 -0.47 0.138745 CDS
Repressed -32 -1.37 0.000187398 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003700

sequence-specific DNA binding transcription factor activity

sequence-specific DNA binding transcription factor activity

Details: 
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
GO Category: 
molecular_function
17
Total items in this category:  
GO:0005622

intracellular

intracellular

Details: 
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO Category: 
cellular_component
65
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.46 U
D3I 3 3 3.83 10.53 I
D3U 3 3 3.83 10.60 U
D5I 9 5 6.00 11.64 I
D5U 17 5 6.00 12.51 U
D7I 18 7 8.14 9.87 I
D7U 19 7 8.14 10.73 U
D14I 4 14 15.63 4.37 I
D14U 4 14 15.63 8.27 U
D17I 3 17 19.15 2.28 I
D17U 3 17 19.15 7.39 U
D21I 4 21 23.23 5.34 I
D21U 4 21 23.23 8.01 U
D24I 3 24 26.60 I
D24U 3 24 26.60 6.90 U
D28I 4 28 30.61 2.16 I
D28U 4 28 30.61 6.89 U