Rv0691c Mycofactocin system transcriptional regulator

Rv0691c (Mycofactocin system transcriptional regulator) is predicted to be co-regulated in modules bicluster_0386 with residual 0.48 and bicluster_0486 with residual 0.55.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.11 and 1,000.00 for bicluster_0386 and 500.00 and 840.00 for bicluster_0486 respectively.

These modules are enriched for following go terms: DNA binding, nucleic acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 101 - 110 of 113
Gene Target Differential Expression Distance Expression pvalue Type
Pantothenate kinase type III, CoaX-like (EC 2.7.1.33)
No -134 0.09 0.999588 CDS
ESX-1 secretion system protein (Rv3616c)
No -100 0.05 0.999588 Primary.TSS
Arsenical pump-driving ATPase (EC 3.6.3.16)
No -139 0.07 0.999588 Antisense.TSS
Arsenical pump-driving ATPase (EC 3.6.3.16)
No -98 0.07 0.999588 Antisense.TSS
Arsenical pump-driving ATPase (EC 3.6.3.16)
No -77 0.07 0.999588 Internal.TSS
No -65 0.06 0.999588 Primary.TSS
Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
No -79 -0.11 0.999588 Primary.TSS
PE-PGRS FAMILY PROTEIN
No -77 -0.19 0.999588 CDS
DNA-dependent DNA polymerase beta chain
No -62 0.09 0.999588 Primary.TSS
Putative ESX-1 secretion system component Rv3869
No -84 0.16 0.999588 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 15.13 U
D3I 3 3 3.83 15.03 I
D3U 3 3 3.83 15.34 U
D5I 9 5 6.00 14.07 I
D5U 17 5 6.00 14.28 U
D7I 18 7 8.14 14.39 I
D7U 19 7 8.14 14.80 U
D14I 4 14 15.63 13.68 I
D14U 4 14 15.63 14.08 U
D17I 3 17 19.15 12.34 I
D17U 3 17 19.15 13.49 U
D21I 4 21 23.23 11.83 I
D21U 4 21 23.23 13.41 U
D24I 3 24 26.60 10.46 I
D24U 3 24 26.60 12.62 U
D28I 4 28 30.61 10.15 I
D28U 4 28 30.61 12.38 U