Rv1144 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 22.214.171.124)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0218 and 560.00 and 11,000.00 for bicluster_0499 respectively.
These modules are enriched for following go terms: aspartic-type endopeptidase activity, aspartic-type peptidase activity.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|Product (LegacyBRC)||Product (RefSeq)|
|PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE_REDUCTASE||short-chain type dehydrogenase/reductase|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.