Rv1215c Cocaine esterase (EC 3.1.1.-)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 430.00 and 1,000.00 for bicluster_0368 and 190.00 and 9,400.00 for bicluster_0456 respectively.
These modules are enriched for following go terms: cellular component biogenesis, cellular component organization or bioge..., protein binding .
This gene is found to be for growth on cholesterol.
|BASS Score||Distance to Tuberculist Start Codon||Internal TSS||New Internal UTR||New Primary UTR||Primary TSS||Re-Annotated Start||Tuberculist Annotated Start|
|Product (LegacyBRC)||Product (RefSeq)|
|Putative uncharacterized protein|
|829||- - - -|
|PATRIC Locus Tag||Enzyme Name||PATRIC Pathways||Transcriptomics|
|Carboxylic ester hydrolases.||Retinol metabolism, 2,4-Dichlorobenzoate degradation, Bisphenol A degradation, Glycerophospholipid metabolism, Tropane, piperidine and pyridine alkaloid biosynthesis, 1,4-Dichlorobenzene degradation, Ascorbate and aldarate metabolism|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.