Rv1353c Transcriptional regulator, TetR family

Rv1353c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0418 with residual 0.49 and bicluster_0511 with residual 0.52.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 7.60 for bicluster_0418 and 670.00 and 6,900.00 for bicluster_0511 respectively.

These modules are enriched for following go terms: phosphopantetheine binding, modified amino acid binding, amide binding, amino acid binding.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 201 - 210 of 238
Gene Target Differential Expression Distance Expression pvalue Type
NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
No -121 -0.08 0.886669 CDS
Possible membrane protein
Induced -137 1.02 0.0033804 CDS
Putative oxidoreductase
No 23 0.05 0.912204 Primary.TSS
No -9 0.21 0.845607 Primary.TSS
Methylated DNA-protein cysteine methyltransferase
No -10 0.2 0.585573 Primary.TSS
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
No 40 -0.42 0.0162153 CDS
UDP-galactose-lipid carrier transferase (EC 2.-.-.-)
No -150 -0.52 0.0151202 Primary.TSS
Sensor histidine kinase MtrB (EC 2.7.3.-)
No -88 -0.16 0.484601 Primary.TSS
DNA-binding response regulator mtrA
No -88 0.2 0.605928 Internal.TSS
Sporulation regulatory protein WhiB
No -3 -0.05 0.952123 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.53 U
D3I 3 3 3.83 11.57 I
D3U 3 3 3.83 12.19 U
D5I 9 5 6.00 8.02 I
D5U 17 5 6.00 10.51 U
D7I 18 7 8.14 7.58 I
D7U 19 7 8.14 10.54 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.74 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 I
D21U 4 21 23.23 8.60 U
D24I 3 24 26.60 I
D24U 3 24 26.60 8.86 U
D28I 4 28 30.61 1.11 I
D28U 4 28 30.61 7.94 U