Rv3223c RNA polymerase sigma-54 factor RpoN

Rv3223c (RNA polymerase sigma-54 factor RpoN) is predicted to be co-regulated in modules bicluster_0224 with residual 0.55 and bicluster_0470 with residual 0.49.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 480.00 and 27.00 for bicluster_0224 and 150.00 and 8,000.00 for bicluster_0470 respectively.

These modules are enriched for following go terms: regulation of cellular process, regulation of biological process, biological regulation .

This gene is found to be for growth on cholesterol.

Mutant available?: Yes

Displaying 21 - 21 of 21
Gene Target Differential Expression Distance Expression pvalue Type
Thioredoxin reductase (EC 1.8.1.9)
Induced 24 2.21 0.0000000000000026 Primary.TSS
not assigned to any KEGG Pathway.
GO:0005515

protein binding

protein binding

Details: 
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO Category: 
molecular_function
135
Total items in this category:  
GO:0006950

response to stress

response to stress

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO Category: 
biological_process
9
Total items in this category:  
GO:0006979

response to oxidative stress

response to oxidative stress

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
GO Category: 
biological_process
13
Total items in this category:  
GO:0009408

response to heat

response to heat

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO Category: 
biological_process
11
Total items in this category:  
GO:0034605

cellular response to heat

cellular response to heat

Details: 
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
GO Category: 
biological_process
2
Total items in this category:  
GO:0006355

regulation of transcription, DNA-dependent

regulation of transcription, DNA-dependent

Details: 
Any process that modulates the frequency, rate or extent of cellular DNA-dependent transcription.
GO Category: 
biological_process
15
Total items in this category:  
GO:0051409

response to nitrosative stress

response to nitrosative stress

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
GO Category: 
biological_process
14
Total items in this category:  
GO:0052572

response to host immune response

response to host immune response

Details: 
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
GO Category: 
biological_process
62
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.11 U
D3I 3 3 3.83 12.34 I
D3U 3 3 3.83 12.50 U
D5I 9 5 6.00 11.70 I
D5U 17 5 6.00 12.90 U
D7I 18 7 8.14 10.93 I
D7U 19 7 8.14 12.56 U
D14I 4 14 15.63 6.07 I
D14U 4 14 15.63 12.09 U
D17I 3 17 19.15 4.47 I
D17U 3 17 19.15 12.25 U
D21I 4 21 23.23 8.86 I
D21U 4 21 23.23 12.37 U
D24I 3 24 26.60 I
D24U 3 24 26.60 12.55 U
D28I 4 28 30.61 4.40 I
D28U 4 28 30.61 12.53 U