Module 444 Residual: 0.53

Title Bicluster Model Residual Score
bicluster_0444 v02 0.53 -9.91
Displaying 1 - 17 of 17
Rv1445c 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type

Details for Rv1445c - 6-phosphogluconolactonase (EC 3.1.1.31), eukaryotic type

GO Terms: GO:0017057, GO:0005886

PATRIC Pathways: Pentose phosphate pathway

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1445c

Tuberculist Genomic Region

Rv1446c OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial

Details for Rv1446c - OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.21 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv1446c

Tuberculist Genomic Region

Rv1447c Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)

Details for Rv1447c - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)

GO Terms: GO:0004345, GO:0005886

PATRIC Pathways: Glutathione metabolism, Pentose phosphate pathway

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1447c

Tuberculist Genomic Region

Rv1449c Transketolase (EC 2.2.1.1)

Details for Rv1449c - Transketolase (EC 2.2.1.1)

GO Terms: GO:0004802, GO:0005576, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Pentose phosphate pathway, Biosynthesis of ansamycins, Carbon fixation in photosynthetic organisms

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1449c

Tuberculist Genomic Region

Rv0444c

Details for Rv0444c -

GO Terms: GO:0005515, GO:0005886, GO:0006417

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0444c

Tuberculist Genomic Region

Rv1121 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)

Details for Rv1121 - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)

GO Terms: GO:0004345, GO:0005886

PATRIC Pathways: Pentose phosphate pathway, Glutathione metabolism

Essentiality: Griffin Essential: 0.09 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1121

Tuberculist Genomic Region

Rv1122 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)

Details for Rv1122 - 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)

GO Terms: GO:0004616, GO:0005886, GO:0040007

PATRIC Pathways: Pentose phosphate pathway, Glutathione metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv1122

Tuberculist Genomic Region

Rv1448c Transaldolase (EC 2.2.1.2)

Details for Rv1448c - Transaldolase (EC 2.2.1.2)

GO Terms: GO:0004801, GO:0005576, GO:0005829, GO:0040007

PATRIC Pathways: Pentose phosphate pathway

Essentiality: Griffin Essential: 0.34 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv1448c

Tuberculist Genomic Region

Rv1547 DNA polymerase III alpha subunit (EC 2.7.7.7)

Details for Rv1547 - DNA polymerase III alpha subunit (EC 2.7.7.7)

GO Terms: GO:0003887, GO:0005886, GO:0040007

PATRIC Pathways: Purine metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1547

Tuberculist Genomic Region

Rv1564c Glycogen debranching enzyme (EC 3.2.1.-)

Details for Rv1564c - Glycogen debranching enzyme (EC 3.2.1.-)

GO Terms: GO:0005975, GO:0043169, GO:0003824

PATRIC Pathways: Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Amino sugar and nucleotide sugar metabolism, Ubiquinone and other terpenoid-quinone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1564c

Tuberculist Genomic Region

Rv1708 Chromosome (plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj

Details for Rv1708 - Chromosome (plasmid) partitioning protein ParA / Sporulation initiation inhibitor protein Soj

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv1708

Tuberculist Genomic Region

Rv1709 Segregation and condensation protein A

Details for Rv1709 - Segregation and condensation protein A

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1709

Tuberculist Genomic Region

Rv1710 Segregation and condensation protein B

Details for Rv1710 - Segregation and condensation protein B

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.85 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv1710

Tuberculist Genomic Region

Rv1711 Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70)

Details for Rv1711 - Ribosomal small subunit pseudouridine synthase A (EC 4.2.1.70)

GO Terms: GO:0040007

PATRIC Pathways: Pyrimidine metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv1711

Tuberculist Genomic Region

Rv1713 GTP-binding protein EngA

Details for Rv1713 - GTP-binding protein EngA

GO Terms: GO:0005525, GO:0005622, GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv1713

Tuberculist Genomic Region

Rv2604c Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit (EC 2.4.2.-)

Details for Rv2604c - Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit (EC 2.4.2.-)

GO Terms: NA

PATRIC Pathways: Purine metabolism, Butirosin and neomycin biosynthesis

Essentiality: Griffin Essential: 0.12 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2604c

Tuberculist Genomic Region

Rv3410c Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

Details for Rv3410c - Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

GO Terms: GO:0003938, GO:0005886

PATRIC Pathways: Purine metabolism, Drug metabolism - other enzymes

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3410c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 230 e-value: 23000
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0016043 | GO:0044085 | GO:0071840 cellular component organization | cellular component biogenesis | cellular component organization or bioge...
Displaying 1 - 20 of 20
GO:0017057 |

6-phosphogluconolactonase activity

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0004345 |

glucose-6-phosphate dehydrogenase activity

GO:0004802 |

transketolase activity

GO:0005576 |

extracellular region

GO:0005829 |

cytosol

GO:0005515 |

protein binding

GO:0006417 |

regulation of translation

GO:0004616 |

phosphogluconate dehydrogenase (decarboxylating) activity

GO:0004801 |

sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

GO:0003887 |

DNA-directed DNA polymerase activity

GO:0005975 |

carbohydrate metabolic process

GO:0043169 |

cation binding

GO:0003824 |

catalytic activity

GO:0005525 |

GTP binding

GO:0005622 |

intracellular

GO:0005618 |

cell wall

GO:0003938 |

IMP dehydrogenase activity