Module 55 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0055 v02 0.58 -13.54
Displaying 1 - 16 of 16
Rv0566c UPF0234 protein YajQ

Details for Rv0566c - UPF0234 protein YajQ

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: 0.39

Go to Gene Page: Rv0566c

Tuberculist Genomic Region

Rv0567 O-methyltransferase

Details for Rv0567 - O-methyltransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0567

Tuberculist Genomic Region

Rv0759c HIT family protein

Details for Rv0759c - HIT family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0759c

Tuberculist Genomic Region

Rv0831c

Details for Rv0831c -

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0831c

Tuberculist Genomic Region

Rv1018c N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)

Details for Rv1018c - N-acetylglucosamine-1-phosphate uridyltransferase (EC 2.7.7.23) / Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157)

GO Terms: GO:0008150, GO:0000287, GO:0003977, GO:0019134, GO:0040007, GO:0070569

PATRIC Pathways: Amino sugar and nucleotide sugar metabolism, Amino sugar and nucleotide sugar metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.15 | In vivo Essential: NA

Go to Gene Page: Rv1018c

Tuberculist Genomic Region

Rv1019 Transcriptional regulator, TetR family

Details for Rv1019 - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1019

Tuberculist Genomic Region

Rv1020 Transcription-repair coupling factor

Details for Rv1020 - Transcription-repair coupling factor

GO Terms: GO:0003700, GO:0008026, GO:0003676, GO:0004386, GO:0005524, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1020

Tuberculist Genomic Region

Rv1021 Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)

Details for Rv1021 - Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)

GO Terms: GO:0005618

PATRIC Pathways: Pyrimidine metabolism, Purine metabolism

Essentiality: Griffin Essential: 0.20 | In vitro Essential: NA | In vivo Essential: 0.38

Go to Gene Page: Rv1021

Tuberculist Genomic Region

Rv1292 Arginyl-tRNA synthetase (EC 6.1.1.19)

Details for Rv1292 - Arginyl-tRNA synthetase (EC 6.1.1.19)

GO Terms: GO:0004814, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1292

Tuberculist Genomic Region

Rv1293 Diaminopimelate decarboxylase (EC 4.1.1.20)

Details for Rv1293 - Diaminopimelate decarboxylase (EC 4.1.1.20)

GO Terms: GO:0008836, GO:0005618, GO:0040007, GO:0042803, GO:0051289

PATRIC Pathways: Lysine biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv1293

Tuberculist Genomic Region

Rv1295 Threonine synthase (EC 4.2.3.1)

Details for Rv1295 - Threonine synthase (EC 4.2.3.1)

GO Terms: GO:0004795, GO:0004795, GO:0005829, GO:0005886, GO:0009088, GO:0030170, GO:0040007, GO:0042803

PATRIC Pathways: Vitamin B6 metabolism, Glycine, serine and threonine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1295

Tuberculist Genomic Region

Rv1746 Probable serine/threonine-protein kinase pknF (EC 2.7.11.1)

Details for Rv1746 - Probable serine/threonine-protein kinase pknF (EC 2.7.11.1)

GO Terms: GO:0000917, GO:0001558, GO:0004672, GO:0004674, GO:0005515, GO:0005829, GO:0005887, GO:0010827, GO:0043085, GO:0043086, GO:0051055

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1746

Tuberculist Genomic Region

Rv2272 Possible membrane protein

Details for Rv2272 - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2272

Tuberculist Genomic Region

Rv2273 Possible membrane protein

Details for Rv2273 - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2273

Tuberculist Genomic Region

Rv2289 CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)

Details for Rv2289 - CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)

GO Terms: GO:0008715, GO:0005576, GO:0005886

PATRIC Pathways: Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2289

Tuberculist Genomic Region

Rv2290 Probable conserved lipoprotein lppOb

Details for Rv2290 - Probable conserved lipoprotein lppOb

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2290

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.58 e-value: 9.5
Displaying 1 - 1 of 1
Predicted regulator PutR for proline utilization, GntR family
regulates 11 modules
Weight: 
0.26
up-regulates
RNA polymerase sigma-54 factor RpoN
regulates 27 modules
Weight: 
0.24
up-regulates
regulates 40 modules
Weight: 
0.17
up-regulates
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
0.15
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 34 of 34
GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0005618 |

cell wall

GO:0008150 |

biological_process

GO:0000287 |

magnesium ion binding

GO:0003977 |

UDP-N-acetylglucosamine diphosphorylase activity

GO:0019134 |

glucosamine-1-phosphate N-acetyltransferase activity

GO:0040007 |

growth

GO:0070569 |

uridylyltransferase activity

GO:0003700 |

sequence-specific DNA binding transcription factor activity

GO:0008026 |

ATP-dependent helicase activity

GO:0003676 |

nucleic acid binding

GO:0004386 |

helicase activity

GO:0005524 |

ATP binding

GO:0004814 |

arginine-tRNA ligase activity

GO:0008836 |

diaminopimelate decarboxylase activity

GO:0042803 |

protein homodimerization activity

GO:0051289 |

protein homotetramerization

GO:0004795 |

threonine synthase activity

GO:0009088 |

threonine biosynthetic process

GO:0030170 |

pyridoxal phosphate binding

GO:0000917 |

barrier septum assembly

GO:0001558 |

regulation of cell growth

GO:0004672 |

protein kinase activity

GO:0004674 |

protein serine/threonine kinase activity

GO:0005515 |

protein binding

GO:0005887 |

integral to plasma membrane

GO:0010827 |

regulation of glucose transport

GO:0043085 |

positive regulation of catalytic activity

GO:0043086 |

negative regulation of catalytic activity

GO:0051055 |

negative regulation of lipid biosynthetic process

GO:0008715 |

CDP-diacylglycerol diphosphatase activity

GO:0005576 |

extracellular region