Module 314 Residual: 0.57

Title Bicluster Model Residual Score
bicluster_0314 v02 0.57 -21.89
Displaying 1 - 17 of 17
Rv0382c Orotate phosphoribosyltransferase (EC 2.4.2.10)

Details for Rv0382c - Orotate phosphoribosyltransferase (EC 2.4.2.10)

GO Terms: GO:0004588

PATRIC Pathways: Drug metabolism - other enzymes, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0382c

Tuberculist Genomic Region

Rv0383c Possible membrane protein

Details for Rv0383c - Possible membrane protein

GO Terms: GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv0383c

Tuberculist Genomic Region

Rv0660c Prevent host death protein, Phd antitoxin

Details for Rv0660c - Prevent host death protein, Phd antitoxin

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.39 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0660c

Tuberculist Genomic Region

Rv1633 Excinuclease ABC subunit B

Details for Rv1633 - Excinuclease ABC subunit B

GO Terms: GO:0004518, GO:0003677, GO:0006289, GO:0004386, GO:0003676, GO:0005524, GO:0005886, GO:0051409

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.26 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1633

Tuberculist Genomic Region

Rv1634 Drug efflux membrane protein

Details for Rv1634 - Drug efflux membrane protein

GO Terms: GO:0015562

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1634

Tuberculist Genomic Region

Rv2366c Magnesium and cobalt efflux protein CorC

Details for Rv2366c - Magnesium and cobalt efflux protein CorC

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2366c

Tuberculist Genomic Region

Rv2367c Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly

Details for Rv2367c - Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly

GO Terms: GO:0003674

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.07 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2367c

Tuberculist Genomic Region

Rv2368c Phosphate starvation-inducible protein PhoH, predicted ATPase

Details for Rv2368c - Phosphate starvation-inducible protein PhoH, predicted ATPase

GO Terms: GO:0003676, GO:0016036, GO:0005524, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2368c

Tuberculist Genomic Region

Rv3010c 6-phosphofructokinase (EC 2.7.1.11)

Details for Rv3010c - 6-phosphofructokinase (EC 2.7.1.11)

GO Terms: GO:0003872, GO:0005618, GO:0005886

PATRIC Pathways: Galactose metabolism, Fructose and mannose metabolism, Pentose phosphate pathway, Methane metabolism, Glycolysis / Gluconeogenesis

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3010c

Tuberculist Genomic Region

Rv3141 PROBABLE NADPH QUINONE OXIDOREDUCTASE FADB4 (NADPH:QUINONE REDUCTASE) (ZETA-CRYSTALLIN) (EC 1.6.5.5)

Details for Rv3141 - PROBABLE NADPH QUINONE OXIDOREDUCTASE FADB4 (NADPH:QUINONE REDUCTASE) (ZETA-CRYSTALLIN) (EC 1.6.5.5)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3141

Tuberculist Genomic Region

Rv0153c Protein tyrosine phosphatase (EC 3.1.3.48)

Details for Rv0153c - Protein tyrosine phosphatase (EC 3.1.3.48)

GO Terms: GO:0004437, GO:0004722, GO:0004725, GO:0005576, GO:0006470, GO:0009405, GO:0004438

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0153c

Tuberculist Genomic Region

Rv0154c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv0154c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0154c

Tuberculist Genomic Region

Rv0724 Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase)

Details for Rv0724 - Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0724

Tuberculist Genomic Region

Rv0902c Sensor-type histidine kinase prrB (EC 2.7.13.3)

Details for Rv0902c - Sensor-type histidine kinase prrB (EC 2.7.13.3)

GO Terms: GO:0004672, GO:0005524, GO:0005887, GO:0042803, GO:0044110, GO:0046777

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0902c

Tuberculist Genomic Region

Rv0903c DNA-binding response regulator

Details for Rv0903c - DNA-binding response regulator

GO Terms: GO:0008150, GO:0008150, GO:0000287, GO:0005509, GO:0005829, GO:0005886, GO:0044110, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0903c

Tuberculist Genomic Region

Rv2052c Exoenzymes regulatory protein AepA in lipid-linked oligosaccharide synthesis cluster

Details for Rv2052c - Exoenzymes regulatory protein AepA in lipid-linked oligosaccharide synthesis cluster

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2052c

Tuberculist Genomic Region

Rv2053c Cytoplasmic membrane protein FsxA

Details for Rv2053c - Cytoplasmic membrane protein FsxA

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2053c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 2e-19 e-value: 0.0000016
Displaying 1 - 1 of 1
Transcriptional regulatory protein
regulates 18 modules
Weight: 
0.32
up-regulates
POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN
regulates 2 modules
Weight: 
0.21
up-regulates
Transcriptional regulatory protein glnR
regulates 5 modules
Weight: 
0.20
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 33 of 33
GO:0004588 |

orotate phosphoribosyltransferase activity

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0004518 |

nuclease activity

GO:0003677 |

DNA binding

GO:0006289 |

nucleotide-excision repair

GO:0004386 |

helicase activity

GO:0003676 |

nucleic acid binding

GO:0005524 |

ATP binding

GO:0051409 |

response to nitrosative stress

GO:0015562 |

efflux transmembrane transporter activity

GO:0003674 |

molecular_function

GO:0016036 |

cellular response to phosphate starvation

GO:0003872 |

6-phosphofructokinase activity

GO:0004437 |

inositol or phosphatidylinositol phosphatase activity

GO:0004722 |

protein serine/threonine phosphatase activity

GO:0004725 |

protein tyrosine phosphatase activity

GO:0005576 |

extracellular region

GO:0006470 |

protein dephosphorylation

GO:0009405 |

pathogenesis

GO:0004438 |

phosphatidylinositol-3-phosphatase activity

GO:0004672 |

protein kinase activity

GO:0005887 |

integral to plasma membrane

GO:0042803 |

protein homodimerization activity

GO:0044110 |

growth involved in symbiotic interaction

GO:0046777 |

protein autophosphorylation

GO:0008150 |

biological_process

GO:0000287 |

magnesium ion binding

GO:0005509 |

calcium ion binding

GO:0005829 |

cytosol

GO:0052572 |

response to host immune response