Module 327 Residual: 0.42

Title Bicluster Model Residual Score
bicluster_0327 v02 0.42 -14.58
Displaying 1 - 13 of 13
Rv0667 DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)

Details for Rv0667 - DNA-directed RNA polymerase beta subunit (EC 2.7.7.6)

GO Terms: GO:0003899, GO:0005618, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Purine metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv0667

Tuberculist Genomic Region

Rv0668 DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)

Details for Rv0668 - DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)

GO Terms: GO:0003899, GO:0005886, GO:0040007

PATRIC Pathways: Purine metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv0668

Tuberculist Genomic Region

Rv2888c Putative amidase amiC (EC 3.5.1.4)

Details for Rv2888c - Putative amidase amiC (EC 3.5.1.4)

GO Terms: GO:0005886

PATRIC Pathways: Phenylalanine metabolism, Tryptophan metabolism, Arginine and proline metabolism, 1,4-Dichlorobenzene degradation, Styrene degradation

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2888c

Tuberculist Genomic Region

Rv2889c Translation elongation factor Ts

Details for Rv2889c - Translation elongation factor Ts

GO Terms: GO:0003746, GO:0006414, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv2889c

Tuberculist Genomic Region

Rv2890c SSU ribosomal protein S2p (SAe)

Details for Rv2890c - SSU ribosomal protein S2p (SAe)

GO Terms: GO:0006412, GO:0005622, GO:0005840, GO:0003735, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2890c

Tuberculist Genomic Region

Rv3417c Heat shock protein 60 family chaperone GroEL

Details for Rv3417c - Heat shock protein 60 family chaperone GroEL

GO Terms: GO:0005524, GO:0044267, GO:0005515, GO:0005618, GO:0005886, GO:0009408, GO:0040007, GO:0051260

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv3417c

Tuberculist Genomic Region

Rv3418c Heat shock protein 60 family co-chaperone GroES

Details for Rv3418c - Heat shock protein 60 family co-chaperone GroES

GO Terms: GO:0005524, GO:0006457, GO:0005576, GO:0005618, GO:0005829, GO:0005886, GO:0009408, GO:0034605, GO:0040007, GO:0006355, GO:0046872, GO:0051260

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv3418c

Tuberculist Genomic Region

Rv3456c LSU ribosomal protein L17p

Details for Rv3456c - LSU ribosomal protein L17p

GO Terms: GO:0003735, GO:0005840, GO:0005622, GO:0006412, GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3456c

Tuberculist Genomic Region

Rv3458c SSU ribosomal protein S4p (S9e)

Details for Rv3458c - SSU ribosomal protein S4p (S9e)

GO Terms: GO:0005622, GO:0003723, GO:0003735, GO:0005840, GO:0006412, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv3458c

Tuberculist Genomic Region

Rv3459c SSU ribosomal protein S11p (S14e)

Details for Rv3459c - SSU ribosomal protein S11p (S14e)

GO Terms: GO:0005622, GO:0005840, GO:0006412, GO:0003735, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.31 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv3459c

Tuberculist Genomic Region

Rv3460c SSU ribosomal protein S13p (S18e)

Details for Rv3460c - SSU ribosomal protein S13p (S18e)

GO Terms: GO:0005622, GO:0003723, GO:0006412, GO:0003735, GO:0005840, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3460c

Tuberculist Genomic Region

Rv3804c Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
Rv3457c DNA-directed RNA polymerase alpha subunit (EC 2.7.7.6)

Details for Rv3457c - DNA-directed RNA polymerase alpha subunit (EC 2.7.7.6)

GO Terms: GO:0003899, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Pyrimidine metabolism, Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv3457c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 440 e-value: 980
Displaying 1 - 1 of 1
regulates 52 modules
Weight: 
-0.25
down-regulates
Single-stranded DNA-binding protein
regulates 26 modules
Weight: 
0.22
up-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.21
up-regulates
RNA polymerase sigma factor SigB
regulates 61 modules
Weight: 
0.13
up-regulates
Transcriptional regulator, BlaI family
regulates 8 modules
Weight: 
-0.11
down-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0033293 | GO:0004713 | GO:1901681 | GO:0004672 | GO:0033218 monocarboxylic acid binding | protein tyrosine kinase activity | sulfur compound binding | protein kinase activity | amide binding
Displaying 1 - 25 of 25
GO:0003899 |

DNA-directed RNA polymerase activity

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0003746 |

translation elongation factor activity

GO:0006414 |

translational elongation

GO:0006412 |

translation

GO:0005622 |

intracellular

GO:0005840 |

ribosome

GO:0003735 |

structural constituent of ribosome

GO:0005524 |

ATP binding

GO:0044267 |

cellular protein metabolic process

GO:0005515 |

protein binding

GO:0009408 |

response to heat

GO:0051260 |

protein homooligomerization

GO:0006457 |

protein folding

GO:0005576 |

extracellular region

GO:0034605 |

cellular response to heat

GO:0006355 |

regulation of transcription, DNA-dependent

GO:0046872 |

metal ion binding

GO:0003723 |

RNA binding

GO:0016747 |

transferase activity, transferring acyl groups other than amino-acyl groups

GO:0044119 |

growth of symbiont in host cell

GO:0044121 |

growth of symbiont in host organelle