Module 336 Residual: 0.51

Title Bicluster Model Residual Score
bicluster_0336 v02 0.51 -36.17
Displaying 1 - 16 of 16
Rv0746 PE-PGRS virulence associated protein

Details for Rv0746 - PE-PGRS virulence associated protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0746

Tuberculist Genomic Region

Rv1552 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)

Details for Rv1552 - Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)

GO Terms: GO:0000104, GO:0005886

PATRIC Pathways: Citrate cycle (TCA cycle), Butanoate metabolism, Oxidative phosphorylation, 2,4-Dichlorobenzoate degradation, Reductive carboxylate cycle (CO2 fixation)

Essentiality: Griffin Essential: 0.28 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1552

Tuberculist Genomic Region

Rv1554 Fumarate reductase subunit C

Details for Rv1554 - Fumarate reductase subunit C

GO Terms: GO:0016020, GO:0006118

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1554

Tuberculist Genomic Region

Rv1555 Fumarate reductase subunit D

Details for Rv1555 - Fumarate reductase subunit D

GO Terms: GO:0006106, GO:0016020

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1555

Tuberculist Genomic Region

Rv1935c Enoyl-CoA hydratase (EC 4.2.1.17) Rv1936 Monooxygenase component A

Details for Rv1936 - Monooxygenase component A

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1936

Tuberculist Genomic Region

Rv1937 Monooxygenase, FAD- and [2Fe-2S]-containing component B

Details for Rv1937 - Monooxygenase, FAD- and [2Fe-2S]-containing component B

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1937

Tuberculist Genomic Region

Rv1938 Monooxygenase component C / Probable epoxide hydrolase EphB (EC 3.3.2.9)

Details for Rv1938 - Monooxygenase component C / Probable epoxide hydrolase EphB (EC 3.3.2.9)

GO Terms: GO:0018742, GO:0042803

PATRIC Pathways: Metabolism of xenobiotics by cytochrome P450

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1938

Tuberculist Genomic Region

Rv1939 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-)
Rv1940 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)

Details for Rv1940 - 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)

GO Terms: NA

PATRIC Pathways: Riboflavin metabolism, Riboflavin metabolism

Essentiality: Griffin Essential: 0.43 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1940

Tuberculist Genomic Region

Rv1941 short-chain type dehydrogenase-reductase

Details for Rv1941 - short-chain type dehydrogenase-reductase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1941

Tuberculist Genomic Region

Rv1290c

Details for Rv1290c -

GO Terms: GO:0005829, GO:0009405

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1290c

Tuberculist Genomic Region

Rv1291c

Details for Rv1291c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1291c

Tuberculist Genomic Region

Rv1578c Probable phiRv1 phage protein

Details for Rv1578c - Probable phiRv1 phage protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.12 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1578c

Tuberculist Genomic Region

Rv1933c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv1933c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0004085

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1933c

Tuberculist Genomic Region

Rv1934c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv1934c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0005618

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1934c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00015 e-value: 0.44
Displaying 1 - 1 of 1
Transcriptional regulator, AraC family
regulates 32 modules
Weight: 
0.20
up-regulates
\transcriptional regulator, Crp/Fnr family\\\""
regulates 21 modules
Weight: 
0.19
up-regulates
Lactate-responsive regulator LldR in Enterobacteria, GntR family
regulates 28 modules
Weight: 
0.19
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 13 of 13
GO:0000104 |

succinate dehydrogenase activity

GO:0005886 |

plasma membrane

GO:0016020 |

membrane

GO:0006118 |

electron transport

GO:0006106 |

fumarate metabolic process

GO:0004300 |

enoyl-CoA hydratase activity

GO:0005829 |

cytosol

GO:0018742 |

epoxide hydrolase B activity

GO:0042803 |

protein homodimerization activity

GO:0009405 |

pathogenesis

GO:0004085 |

butyryl-CoA dehydrogenase activity

GO:0005618 |

cell wall