Module 337 Residual: 0.50

Title Bicluster Model Residual Score
bicluster_0337 v02 0.50 -20.03
Displaying 1 - 18 of 18
Rv0847 PROBABLE LIPOPROTEIN LPQS

Details for Rv0847 - PROBABLE LIPOPROTEIN LPQS

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0847

Tuberculist Genomic Region

Rv0846c Multicopper oxidase

Details for Rv0846c - Multicopper oxidase

GO Terms: GO:0016491, GO:0005507

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0846c

Tuberculist Genomic Region

Rv0848 Cysteine synthase (EC 2.5.1.47)

Details for Rv0848 - Cysteine synthase (EC 2.5.1.47)

GO Terms: GO:0004124, GO:0005618

PATRIC Pathways: Cysteine and methionine metabolism, Sulfur metabolism

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0848

Tuberculist Genomic Region

Rv0849 PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN

Details for Rv0849 - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0849

Tuberculist Genomic Region

Rv0850 PUTATIVE TRANSPOSASE (FRAGMENT)

Details for Rv0850 - PUTATIVE TRANSPOSASE (FRAGMENT)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0850

Tuberculist Genomic Region

Rv1994c Transcriptional regulator, ArsR family

Details for Rv1994c - Transcriptional regulator, ArsR family

GO Terms: GO:0010288, GO:0016564, GO:0032791, GO:0042803, GO:0046686, GO:0046870

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.36 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1994c

Tuberculist Genomic Region

Rv1995

Details for Rv1995 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1995

Tuberculist Genomic Region

Rv3529c

Details for Rv3529c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.56 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3529c

Tuberculist Genomic Region

Rv3530c Short-chain dehydrogenase/reductase SDR

Details for Rv3530c - Short-chain dehydrogenase/reductase SDR

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.07 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3530c

Tuberculist Genomic Region

Rv3531c

Details for Rv3531c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3531c

Tuberculist Genomic Region

Rv3534c 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)

Details for Rv3534c - 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)

GO Terms: NA

PATRIC Pathways: Biphenyl degradation, Toluene and xylene degradation, Phenylalanine metabolism, Benzoate degradation via hydroxylation

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: 0.39

Go to Gene Page: Rv3534c

Tuberculist Genomic Region

Rv3535c Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol

Details for Rv3535c - Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol

GO Terms: NA

PATRIC Pathways: Toluene and xylene degradation, Butanoate metabolism, Biphenyl degradation, Benzoate degradation via hydroxylation, Pyruvate metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3535c

Tuberculist Genomic Region

Rv3536c 2-keto-4-pentenoate hydratase (EC 4.2.1.-)

Details for Rv3536c - 2-keto-4-pentenoate hydratase (EC 4.2.1.-)

GO Terms: GO:0003824, GO:0008152, GO:0016829, GO:0006725

PATRIC Pathways: Toluene and xylene degradation, Benzoate degradation via hydroxylation, Phenylalanine metabolism, Biphenyl degradation

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3536c

Tuberculist Genomic Region

Rv3537 3-oxosteroid 1-dehydrogenase (EC 1.3.99.4)

Details for Rv3537 - 3-oxosteroid 1-dehydrogenase (EC 1.3.99.4)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.07 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3537

Tuberculist Genomic Region

Rv3538 Enoyl-CoA hydratase

Details for Rv3538 - Enoyl-CoA hydratase

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.34 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv3538

Tuberculist Genomic Region

Rv3567c Nitrilotriacetate monooxygenase component B (EC 1.14.13.-)
Rv3569c 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-)

Details for Rv3569c - 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase (EC 3.7.1.-)

GO Terms: GO:0005618, GO:0005886, GO:0034820, GO:0042803, GO:0044117

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3569c

Tuberculist Genomic Region

Rv3571 Phenylacetate-CoA oxygenase/reductase, PaaK subunit

Details for Rv3571 - Phenylacetate-CoA oxygenase/reductase, PaaK subunit

GO Terms: GO:0001666, GO:0051409

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3571

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 1.2e-19 e-value: 0.000000026
Displaying 1 - 1 of 1
Transcriptional regulator kstR (Rv3574), TetR family
regulates 3 modules
Weight: 
0.20
up-regulates
Transcriptional regulator, ArsR family
regulates 25 modules
Weight: 
0.15
up-regulates
Transcriptional regulator, TetR family
regulates 12 modules
Weight: 
-0.15
down-regulates
Adenylyl cyclase class-3/4/guanylyl cyclase / Disease resistance domain-containing protein / Tetratricopeptide repeat-containing protein / Transcriptional regulator, LuxR family
regulates 11 modules
Weight: 
0.12
up-regulates
Two-component response regulator
regulates 21 modules
Weight: 
-0.11
down-regulates
Transcriptional regulator, FUR family
regulates 9 modules
Weight: 
0.10
up-regulates
Transcriptional regulator, ArsR family
regulates 19 modules
Weight: 
0.08
up-regulates
Transcriptional regulator, TetR family
regulates 2 modules
Weight: 
0.07
up-regulates
regulates 13 modules
Weight: 
0.06
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0004070 aspartate carbamoyltransferase activity
Displaying 1 - 21 of 21
GO:0016491 |

oxidoreductase activity

GO:0005507 |

copper ion binding

GO:0004124 |

cysteine synthase activity

GO:0005618 |

cell wall

GO:0010288 |

response to lead ion

GO:0016564 |

transcription repressor activity

GO:0032791 |

lead ion binding

GO:0042803 |

protein homodimerization activity

GO:0046686 |

response to cadmium ion

GO:0046870 |

cadmium ion binding

GO:0005886 |

plasma membrane

GO:0003824 |

catalytic activity

GO:0008152 |

metabolic process

GO:0016829 |

lyase activity

GO:0006725 |

cellular aromatic compound metabolic process

GO:0040007 |

growth

GO:0034820 |

4,9-DSHA hydrolase activity

GO:0044117 |

growth of symbiont in host

GO:0001666 |

response to hypoxia

GO:0051409 |

response to nitrosative stress