Module 342 Residual: 0.54

Title Bicluster Model Residual Score
bicluster_0342 v02 0.54 -12.76
Displaying 1 - 13 of 13
Rv0295c Sulfotransferase

Details for Rv0295c - Sulfotransferase

GO Terms: GO:0005618, GO:0005886, GO:0005991, GO:0008146, GO:0042803, GO:0046506, GO:0050427, GO:0050656

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0295c

Tuberculist Genomic Region

Rv0296c Choline-sulfatase (EC 3.1.6.6)

Details for Rv0296c - Choline-sulfatase (EC 3.1.6.6)

GO Terms: GO:0005618

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0296c

Tuberculist Genomic Region

Rv0546c

Details for Rv0546c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0546c

Tuberculist Genomic Region

Rv1426c Lipase (EC 3.1.1.3)

Details for Rv1426c - Lipase (EC 3.1.1.3)

GO Terms: GO:0005886, GO:0052572

PATRIC Pathways: Glycerolipid metabolism

Essentiality: Griffin Essential: 0.60 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1426c

Tuberculist Genomic Region

Rv1427c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv1427c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0004467

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1427c

Tuberculist Genomic Region

Rv1428c acyltransferase family protein

Details for Rv1428c - acyltransferase family protein

GO Terms: GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1428c

Tuberculist Genomic Region

Rv2294 Putative cystathionine beta-lyase (EC 4.4.1.8)

Details for Rv2294 - Putative cystathionine beta-lyase (EC 4.4.1.8)

GO Terms: GO:0005886

PATRIC Pathways: Cysteine and methionine metabolism, Selenoamino acid metabolism, Nitrogen metabolism, Sulfur metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2294

Tuberculist Genomic Region

Rv0317c Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46)

Details for Rv0317c - Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46)

GO Terms: GO:0008889

PATRIC Pathways: Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0317c

Tuberculist Genomic Region

Rv0533c \3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41)\\\""

Details for Rv0533c - \3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.41)\\\""

GO Terms: GO:0000062, GO:0004315, GO:0005515, GO:0006633, GO:0008610, GO:0030497, GO:0033818, GO:0035336, GO:0042803

PATRIC Pathways: Fatty acid biosynthesis

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0533c

Tuberculist Genomic Region

Rv0554 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20)

Details for Rv0554 - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20)

GO Terms: GO:0047570

PATRIC Pathways: Ubiquinone and other terpenoid-quinone biosynthesis

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0554

Tuberculist Genomic Region

Rv0568 Cytochrome P450 135B1

Details for Rv0568 - Cytochrome P450 135B1

GO Terms: GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0568

Tuberculist Genomic Region

Rv2523c Holo-[acyl-carrier protein] synthase (EC 2.7.8.7)

Details for Rv2523c - Holo-[acyl-carrier protein] synthase (EC 2.7.8.7)

GO Terms: NA

PATRIC Pathways: Pantothenate and CoA biosynthesis

Essentiality: Griffin Essential: 0.12 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2523c

Tuberculist Genomic Region

Rv3598c Lysyl-tRNA synthetase (class II) (EC 6.1.1.6)

Details for Rv3598c - Lysyl-tRNA synthetase (class II) (EC 6.1.1.6)

GO Terms: GO:0004824, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv3598c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 37 e-value: 4800
Displaying 1 - 1 of 1
RNA polymerase sigma factor SigB
regulates 18 modules
Weight: 
-0.23
down-regulates
Transcriptional regulator, TetR family
regulates 16 modules
Weight: 
0.17
up-regulates
RNA polymerase sigma-54 factor RpoN
regulates 27 modules
Weight: 
0.15
up-regulates
Possible transcriptional regulatory protein
regulates 46 modules
Weight: 
0.12
up-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.10
up-regulates
Transcriptional regulator, MarR family
regulates 11 modules
Weight: 
0.08
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0009082 | GO:0009081 | GO:0005829 | GO:0044445 branched-chain amino acid biosynthetic p... | branched-chain amino acid metabolic proc... | cytosol | cytosolic part
Displaying 1 - 24 of 24
GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0005991 |

trehalose metabolic process

GO:0008146 |

sulfotransferase activity

GO:0042803 |

protein homodimerization activity

GO:0046506 |

sulfolipid biosynthetic process

GO:0050427 |

3'-phosphoadenosine 5'-phosphosulfate metabolic process

GO:0050656 |

3'-phosphoadenosine 5'-phosphosulfate binding

GO:0052572 |

response to host immune response

GO:0004467 |

long-chain fatty acid-CoA ligase activity

GO:0008889 |

glycerophosphodiester phosphodiesterase activity

GO:0000062 |

fatty-acyl-CoA binding

GO:0004315 |

3-oxoacyl-[acyl-carrier-protein] synthase activity

GO:0005515 |

protein binding

GO:0006633 |

fatty acid biosynthetic process

GO:0008610 |

lipid biosynthetic process

GO:0030497 |

fatty acid elongation

GO:0033818 |

beta-ketoacyl-acyl-carrier-protein synthase III activity

GO:0035336 |

long-chain fatty-acyl-CoA metabolic process

GO:0047570 |

3-oxoadipate enol-lactonase activity

GO:0005829 |

cytosol

GO:0004824 |

lysine-tRNA ligase activity

GO:0040007 |

growth