Module 351 Residual: 0.53

Title Bicluster Model Residual Score
bicluster_0351 v02 0.53 -19.66
Displaying 1 - 17 of 17
Rv1003 rRNA small subunit methyltransferase I

Details for Rv1003 - rRNA small subunit methyltransferase I

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1003

Tuberculist Genomic Region

Rv3432c Glutamate decarboxylase (EC 4.1.1.15)

Details for Rv3432c - Glutamate decarboxylase (EC 4.1.1.15)

GO Terms: NA

PATRIC Pathways: Butanoate metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3432c

Tuberculist Genomic Region

Rv3813c Cof family hydrolase

Details for Rv3813c - Cof family hydrolase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3813c

Tuberculist Genomic Region

Rv3815c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3815c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0003841

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3815c

Tuberculist Genomic Region

Rv3817 aminoglycoside 3'-phosphotransferase

Details for Rv3817 - aminoglycoside 3'-phosphotransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3817

Tuberculist Genomic Region

Rv1914c

Details for Rv1914c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1914c

Tuberculist Genomic Region

Rv1915 Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2

Details for Rv1915 - Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2

GO Terms: GO:0004451, GO:0004451, GO:0006097, GO:0046421

PATRIC Pathways: Glyoxylate and dicarboxylate metabolism

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1915

Tuberculist Genomic Region

Rv1916 Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2

Details for Rv1916 - Isocitrate lyase (EC 4.1.3.1), group III, Mycobacterial type ICL2

GO Terms: GO:0004451

PATRIC Pathways: Glyoxylate and dicarboxylate metabolism

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1916

Tuberculist Genomic Region

Rv2298 Aldo/keto reductase

Details for Rv2298 - Aldo/keto reductase

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.88 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2298

Tuberculist Genomic Region

Rv2609c FIG019327: Probable conserved membrane protein

Details for Rv2609c - FIG019327: Probable conserved membrane protein

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.10 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2609c

Tuberculist Genomic Region

Rv2610c Phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57)

Details for Rv2610c - Phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57)

GO Terms: GO:0000030, GO:0000287, GO:0005886, GO:0043750

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2610c

Tuberculist Genomic Region

Rv2611c Lauroyl/myristoyl acyltransferase involved in lipid A biosynthesis (Lauroyl/myristoyl acyltransferase)

Details for Rv2611c - Lauroyl/myristoyl acyltransferase involved in lipid A biosynthesis (Lauroyl/myristoyl acyltransferase)

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.07 | In vivo Essential: NA

Go to Gene Page: Rv2611c

Tuberculist Genomic Region

Rv2613c FIG049476: HIT family protein

Details for Rv2613c - FIG049476: HIT family protein

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.13 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv2613c

Tuberculist Genomic Region

Rv2614c Threonyl-tRNA synthetase (EC 6.1.1.3)

Details for Rv2614c - Threonyl-tRNA synthetase (EC 6.1.1.3)

GO Terms: GO:0004829, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv2614c

Tuberculist Genomic Region

Rv2895c Iron utilization protein

Details for Rv2895c - Iron utilization protein

GO Terms: GO:0005886, GO:0010106, GO:0015891

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2895c

Tuberculist Genomic Region

Rv3814c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3814c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0005886

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3814c

Tuberculist Genomic Region

Rv3816c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3816c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0003841, GO:0005886

PATRIC Pathways: Glycerophospholipid metabolism, Glycerolipid metabolism

Essentiality: Griffin Essential: 0.20 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3816c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000064 e-value: 0.02
Displaying 1 - 1 of 1
Possible transcriptional regulatory protein
regulates 46 modules
Weight: 
0.18
up-regulates
Phosphate transport system regulatory protein PhoU
regulates 11 modules
Weight: 
0.17
up-regulates
RNA polymerase sigma factor SigB
regulates 61 modules
Weight: 
0.14
up-regulates
Regulator of polyketide synthase expression
regulates 5 modules
Weight: 
0.14
up-regulates
Transcriptional regulator, TetR family
regulates 23 modules
Weight: 
0.11
up-regulates
regulates 40 modules
Weight: 
0.09
up-regulates
Transcriptional regulator, TetR family
regulates 10 modules
Weight: 
0.08
up-regulates
Transcriptional regulator, TetR family
regulates 9 modules
Weight: 
0.03
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 14 of 14
GO:0005886 |

plasma membrane

GO:0003841 |

1-acylglycerol-3-phosphate O-acyltransferase activity

GO:0004451 |

isocitrate lyase activity

GO:0006097 |

glyoxylate cycle

GO:0046421 |

methylisocitrate lyase activity

GO:0005618 |

cell wall

GO:0000030 |

mannosyltransferase activity

GO:0000287 |

magnesium ion binding

GO:0043750 |

phosphatidylinositol alpha-mannosyltransferase activity

GO:0040007 |

growth

GO:0004829 |

threonine-tRNA ligase activity

GO:0010106 |

cellular response to iron ion starvation

GO:0015891 |

siderophore transport