Module 417 Residual: 0.42

Title Bicluster Model Residual Score
bicluster_0417 v02 0.42 -18.75
Displaying 1 - 18 of 18
Rv1996 Universal stress protein family

Details for Rv1996 - Universal stress protein family

GO Terms: GO:0005618, GO:0005886, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1996

Tuberculist Genomic Region

Rv0569

Details for Rv0569 -

GO Terms: GO:0001666, GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0569

Tuberculist Genomic Region

Rv1733c Possible membrane protein

Details for Rv1733c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1733c

Tuberculist Genomic Region

Rv1736c Respiratory nitrate reductase NarX

Details for Rv1736c - Respiratory nitrate reductase NarX

GO Terms: GO:0008940, GO:0001666, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1736c

Tuberculist Genomic Region

Rv1737c Nitrate/nitrite transporter

Details for Rv1737c - Nitrate/nitrite transporter

GO Terms: GO:0001666, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1737c

Tuberculist Genomic Region

Rv1738

Details for Rv1738 -

GO Terms: GO:0005829, GO:0005886, GO:0040007, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: 0.16 | In vivo Essential: NA

Go to Gene Page: Rv1738

Tuberculist Genomic Region

Rv2005c Universal stress protein family

Details for Rv2005c - Universal stress protein family

GO Terms: GO:0001666, GO:0005618, GO:0005886, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2005c

Tuberculist Genomic Region

Rv2006 Trehalose-6-phosphate phosphatase (EC 3.1.3.12)

Details for Rv2006 - Trehalose-6-phosphate phosphatase (EC 3.1.3.12)

GO Terms: GO:0005576, GO:0005618, GO:0005886, GO:0004805

PATRIC Pathways: Ubiquinone and other terpenoid-quinone biosynthesis, Amino sugar and nucleotide sugar metabolism, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2006

Tuberculist Genomic Region

Rv2030c Erythromycin esterase homolog

Details for Rv2030c - Erythromycin esterase homolog

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2030c

Tuberculist Genomic Region

Rv2031c 14 kDa antigen (16 kDa antigen) (HSP 16.3)

Details for Rv2031c - 14 kDa antigen (16 kDa antigen) (HSP 16.3)

GO Terms: GO:0001666, GO:0005618, GO:0005829, GO:0005886, GO:0006457, GO:0009267, GO:0009408, GO:0010039, GO:0044121, GO:0044183, GO:0045926, GO:0046777, GO:0051260, GO:0051409, GO:0052572, GO:0071456, GO:0071500, GO:0075136

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2031c

Tuberculist Genomic Region

Rv2032 Dinucleotide-utilizing enzyme, Rv2032/acg (acr-coregulated gene)

Details for Rv2032 - Dinucleotide-utilizing enzyme, Rv2032/acg (acr-coregulated gene)

GO Terms: GO:0001666, GO:0005829, GO:0005886, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.70 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2032

Tuberculist Genomic Region

Rv2623 Universal stress protein family

Details for Rv2623 - Universal stress protein family

GO Terms: GO:0001666, GO:0005618, GO:0005829, GO:0005886, GO:0040007, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv2623

Tuberculist Genomic Region

Rv2626c CBS domain protein

Details for Rv2626c - CBS domain protein

GO Terms: GO:0001666, GO:0005829, GO:0005886, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2626c

Tuberculist Genomic Region

Rv2627c

Details for Rv2627c -

GO Terms: GO:0005886, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.30 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2627c

Tuberculist Genomic Region

Rv2628

Details for Rv2628 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2628

Tuberculist Genomic Region

Rv3132c Two component system sensor histidine kinase DevS

Details for Rv3132c - Two component system sensor histidine kinase DevS

GO Terms: GO:0000287, GO:0004672, GO:0005524, GO:0005886, GO:0019825, GO:0019826, GO:0020037, GO:0040007, GO:0046777, GO:0051776, GO:0070025, GO:0070026, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv3132c

Tuberculist Genomic Region

Rv3133c Two component transcriptional regulatory protein DevR

Details for Rv3133c - Two component transcriptional regulatory protein DevR

GO Terms: GO:0008150, GO:0001666, GO:0003677, GO:0003700, GO:0005829, GO:0005886, GO:0009405, GO:0045893, GO:0071500

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3133c

Tuberculist Genomic Region

Rv3134c Universal stress protein family

Details for Rv3134c - Universal stress protein family

GO Terms: GO:0001666, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3134c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 3.9e-21 e-value: 0.00018
Displaying 1 - 1 of 1
Sporulation regulatory protein WhiB
regulates 11 modules
Weight: 
-0.31
down-regulates
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
-0.17
down-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
-0.16
down-regulates
Transcriptional regulator, AsnC family
regulates 7 modules
Weight: 
0.12
up-regulates
Two-component response regulator
regulates 21 modules
Weight: 
0.11
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 37 of 37
GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0071500 |

cellular response to nitrosative stress

GO:0001666 |

response to hypoxia

GO:0005829 |

cytosol

GO:0008940 |

nitrate reductase activity

GO:0040007 |

growth

GO:0052572 |

response to host immune response

GO:0005576 |

extracellular region

GO:0004805 |

trehalose-phosphatase activity

GO:0006457 |

protein folding

GO:0009267 |

cellular response to starvation

GO:0009408 |

response to heat

GO:0010039 |

response to iron ion

GO:0044121 |

growth of symbiont in host organelle

GO:0044183 |

protein binding involved in protein folding

GO:0045926 |

negative regulation of growth

GO:0046777 |

protein autophosphorylation

GO:0051260 |

protein homooligomerization

GO:0051409 |

response to nitrosative stress

GO:0071456 |

cellular response to hypoxia

GO:0075136 |

response to host

GO:0000287 |

magnesium ion binding

GO:0004672 |

protein kinase activity

GO:0005524 |

ATP binding

GO:0019825 |

oxygen binding

GO:0019826 |

oxygen sensor activity

GO:0020037 |

heme binding

GO:0051776 |

detection of redox state

GO:0070025 |

carbon monoxide binding

GO:0070026 |

nitric oxide binding

GO:0008150 |

biological_process

GO:0003677 |

DNA binding

GO:0003700 |

sequence-specific DNA binding transcription factor activity

GO:0009405 |

pathogenesis

GO:0045893 |

positive regulation of transcription, DNA-dependent