Module 448 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0448 v02 0.58 -12.34
Displaying 1 - 15 of 15
Rv1360 Oxidoreductase

Details for Rv1360 - Oxidoreductase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1360

Tuberculist Genomic Region

Rv3682 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Details for Rv3682 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

GO Terms: GO:0008955, GO:0005829, GO:0005886

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.45 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3682

Tuberculist Genomic Region

Rv3778c Cysteine desulfurase (EC 2.8.1.7)

Details for Rv3778c - Cysteine desulfurase (EC 2.8.1.7)

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Thiamine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv3778c

Tuberculist Genomic Region

Rv3779

Details for Rv3779 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3779

Tuberculist Genomic Region

Rv0288 10 kDa antigen CFP7

Details for Rv0288 - 10 kDa antigen CFP7

GO Terms: GO:0005515

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0288

Tuberculist Genomic Region

Rv0500 Pyrroline-5-carboxylate reductase (EC 1.5.1.2)

Details for Rv0500 - Pyrroline-5-carboxylate reductase (EC 1.5.1.2)

GO Terms: GO:0004735, GO:0005886, GO:0040007

PATRIC Pathways: Arginine and proline metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv0500

Tuberculist Genomic Region

Rv0501 UDP-glucose 4-epimerase (EC 5.1.3.2)

Details for Rv0501 - UDP-glucose 4-epimerase (EC 5.1.3.2)

GO Terms: GO:0005576, GO:0005829, GO:0005886

PATRIC Pathways: Galactose metabolism, Amino sugar and nucleotide sugar metabolism

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0501

Tuberculist Genomic Region

Rv0543c

Details for Rv0543c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.17 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0543c

Tuberculist Genomic Region

Rv1630 SSU ribosomal protein S1p

Details for Rv1630 - SSU ribosomal protein S1p

GO Terms: GO:0003723, GO:0005618, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv1630

Tuberculist Genomic Region

Rv2462c Cell division trigger factor (EC 5.2.1.8)

Details for Rv2462c - Cell division trigger factor (EC 5.2.1.8)

GO Terms: GO:0008150, GO:0008150, GO:0008150, GO:0005829, GO:0005886, GO:0009267

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2462c

Tuberculist Genomic Region

Rv2903c Signal peptidase I (EC 3.4.21.89)

Details for Rv2903c - Signal peptidase I (EC 3.4.21.89)

GO Terms: GO:0008236, GO:0006508, GO:0005576, GO:0005887, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv2903c

Tuberculist Genomic Region

Rv3019c 10 kDa antigen CFP7

Details for Rv3019c - 10 kDa antigen CFP7

GO Terms: GO:0005515

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3019c

Tuberculist Genomic Region

Rv3248c Adenosylhomocysteinase (EC 3.3.1.1)

Details for Rv3248c - Adenosylhomocysteinase (EC 3.3.1.1)

GO Terms: GO:0004013, GO:0005576, GO:0005829, GO:0005886, GO:0040007, GO:0046085, GO:0070403

PATRIC Pathways: Cysteine and methionine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv3248c

Tuberculist Genomic Region

Rv3780

Details for Rv3780 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3780

Tuberculist Genomic Region

Rv3804c Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 2.8 e-value: 7
Displaying 1 - 1 of 1
regulates 52 modules
Weight: 
-0.20
down-regulates
RNA polymerase sigma factor SigB
regulates 61 modules
Weight: 
0.13
up-regulates
Transcriptional regulator, TetR family
regulates 32 modules
Weight: 
0.12
up-regulates
Single-stranded DNA-binding protein
regulates 26 modules
Weight: 
0.11
up-regulates
Transcriptional regulator, TetR family
regulates 14 modules
Weight: 
0.11
up-regulates
response regulator
regulates 69 modules
Weight: 
0.09
up-regulates
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
0.08
up-regulates
regulates 43 modules
Weight: 
0.08
up-regulates
\Transcriptional regulator, TetR family\\\""
regulates 32 modules
Weight: 
0.07
up-regulates
regulates 22 modules
Weight: 
0.05
up-regulates
regulates 26 modules
Weight: 
0.04
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 21 of 21
GO:0008955 |

peptidoglycan glycosyltransferase activity

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0005515 |

protein binding

GO:0004735 |

pyrroline-5-carboxylate reductase activity

GO:0005576 |

extracellular region

GO:0003723 |

RNA binding

GO:0005618 |

cell wall

GO:0008150 |

biological_process

GO:0009267 |

cellular response to starvation

GO:0008236 |

serine-type peptidase activity

GO:0006508 |

proteolysis

GO:0005887 |

integral to plasma membrane

GO:0004013 |

adenosylhomocysteinase activity

GO:0046085 |

adenosine metabolic process

GO:0070403 |

NAD+ binding

GO:0016747 |

transferase activity, transferring acyl groups other than amino-acyl groups

GO:0044119 |

growth of symbiont in host cell

GO:0044121 |

growth of symbiont in host organelle