Module 472 Residual: 0.59

Title Bicluster Model Residual Score
bicluster_0472 v02 0.59 -10.03
Displaying 1 - 19 of 19
Rv1747 Probable conserved transmembrane ATP-binding protein ABC transporter

Details for Rv1747 - Probable conserved transmembrane ATP-binding protein ABC transporter

GO Terms: GO:0005515, GO:0005618, GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1747

Tuberculist Genomic Region

Rv3875 6 kDa early secretory antigenic target ESAT-6 (EsxA)

Details for Rv3875 - 6 kDa early secretory antigenic target ESAT-6 (EsxA)

GO Terms: GO:0005515, GO:0005576, GO:0005618, GO:0005737, GO:0005886, GO:0009405, GO:0042803, GO:0046812, GO:0052027, GO:0052083

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.15 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3875

Tuberculist Genomic Region

Rv3876 RD1 region associated protein Rv3876

Details for Rv3876 - RD1 region associated protein Rv3876

GO Terms: GO:0005886, GO:0009405

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: 0.33

Go to Gene Page: Rv3876

Tuberculist Genomic Region

Rv1248c Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) / 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)

Details for Rv1248c - Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) / 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2)

GO Terms: GO:0000287, GO:0005515, GO:0005886, GO:0006099, GO:0008683, GO:0009055, GO:0040007, GO:0045254, GO:0055114, GO:0004591

PATRIC Pathways: Lysine degradation, Citrate cycle (TCA cycle), Lysine degradation, Citrate cycle (TCA cycle), Tryptophan metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1248c

Tuberculist Genomic Region

Rv1333 possible hydrolase

Details for Rv1333 - possible hydrolase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv1333

Tuberculist Genomic Region

Rv1335 9.5 kDa culture filtrate antigen Cfp10A

Details for Rv1335 - 9.5 kDa culture filtrate antigen Cfp10A

GO Terms: GO:0019344, GO:0043234

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1335

Tuberculist Genomic Region

Rv2081c

Details for Rv2081c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2081c

Tuberculist Genomic Region

Rv2082

Details for Rv2082 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.45 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2082

Tuberculist Genomic Region

Rv2083

Details for Rv2083 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2083

Tuberculist Genomic Region

Rv2163c Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)

Details for Rv2163c - Cell division protein FtsI [Peptidoglycan synthetase] (EC 2.4.1.129)

GO Terms: GO:0008955, GO:0005515, GO:0005576, GO:0040007

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv2163c

Tuberculist Genomic Region

Rv2164c FIG034299: proline rich membrane protein

Details for Rv2164c - FIG034299: proline rich membrane protein

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv2164c

Tuberculist Genomic Region

Rv2345 Possible membrane protein

Details for Rv2345 - Possible membrane protein

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2345

Tuberculist Genomic Region

Rv2365c

Details for Rv2365c -

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: 0.15 | In vivo Essential: NA

Go to Gene Page: Rv2365c

Tuberculist Genomic Region

Rv3676 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Details for Rv3676 - cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

GO Terms: GO:0003677, GO:0005886, GO:0045892, GO:0030552, GO:0040007, GO:0042803, GO:0045893

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.31 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3676

Tuberculist Genomic Region

Rv3719 FAD/FMN-containing dehydrogenases

Details for Rv3719 - FAD/FMN-containing dehydrogenases

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3719

Tuberculist Genomic Region

Rv3720 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

Details for Rv3720 - Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3720

Tuberculist Genomic Region

Rv3877 Putative ESX-1 secretion system component Rv3877

Details for Rv3877 - Putative ESX-1 secretion system component Rv3877

GO Terms: GO:0042783, GO:0044110, GO:0044117, GO:0052027, GO:0052083

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: 0.13

Go to Gene Page: Rv3877

Tuberculist Genomic Region

Rv3884c Cell division protein FtsH (EC 3.4.24.-)

Details for Rv3884c - Cell division protein FtsH (EC 3.4.24.-)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.42 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3884c

Tuberculist Genomic Region

Rv3910 Proposed peptidoglycan lipid II flippase MurJ

Details for Rv3910 - Proposed peptidoglycan lipid II flippase MurJ

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.18

Go to Gene Page: Rv3910

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0071 e-value: 1.7
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 31 of 31
GO:0005515 |

protein binding

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005576 |

extracellular region

GO:0005737 |

cytoplasm

GO:0005886 |

plasma membrane

GO:0009405 |

pathogenesis

GO:0042803 |

protein homodimerization activity

GO:0046812 |

host cell surface binding

GO:0052027 |

modulation by symbiont of host signal transduction pathway

GO:0052083 |

negative regulation by symbiont of host cell-mediated immune response

GO:0000287 |

magnesium ion binding

GO:0006099 |

tricarboxylic acid cycle

GO:0008683 |

2-oxoglutarate decarboxylase activity

GO:0009055 |

electron carrier activity

GO:0040007 |

growth

GO:0045254 |

pyruvate dehydrogenase complex

GO:0055114 |

oxidation-reduction process

GO:0004591 |

oxoglutarate dehydrogenase (succinyl-transferring) activity

GO:0019344 |

cysteine biosynthetic process

GO:0043234 |

protein complex

GO:0008955 |

peptidoglycan glycosyltransferase activity

GO:0005887 |

integral to plasma membrane

GO:0003677 |

DNA binding

GO:0045892 |

negative regulation of transcription, DNA-dependent

GO:0030552 |

cAMP binding

GO:0045893 |

positive regulation of transcription, DNA-dependent

GO:0042783 |

active evasion of host immune response

GO:0044110 |

growth involved in symbiotic interaction

GO:0044117 |

growth of symbiont in host